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. 1985 Aug;82(15):5203-7.
doi: 10.1073/pnas.82.15.5203.

Morphine and other opiates from beef brain and adrenal

A Goldstein, R W Barrett, I F James, L I Lowney, C J Weitz, L L Knipmeyer, H Rapoport

Morphine and other opiates from beef brain and adrenal

A Goldstein et al. Proc Natl Acad Sci U S A. 1985 Aug.

Abstract

We describe nonpeptide opioids found in extracts of beef hypothalamus and adrenal, which are recognized by antisera raised against morphine. Four have been purified to homogeneity. One is morphine. The structures of the other three have not been determined yet. None of them are derived from morphine or normorphine after extraction from the tissues. It is not known whether the opiates described here are of endogenous or exogenous origin.

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