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. 2024 Apr 11;187(8):1822-1822.e1.
doi: 10.1016/j.cell.2024.03.018.

Self-amplifying RNA COVID-19 vaccine

Christopher J Wayne  1 , Anna K Blakney  2
Affiliations
Free article

Self-amplifying RNA COVID-19 vaccine

Christopher J Wayne et al. Cell. .
Free article

Abstract

In November 2023, Japan's Ministry of Health, Labour and Welfare granted regulatory approval of ARCT-154, a self-amplifying RNA COVID-19 vaccine developed by Arcturus Therapeutics. Clinical trials showed comparable safety and efficacy using a lower dose compared to the mRNA vaccine BNT162b2. To view this Bench-to-Bedside, open or download the PDF.

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