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Meta-Analysis
. 2024 May;144(5):2449-2459.
doi: 10.1007/s00402-024-05292-8. Epub 2024 Apr 13.

Comparative analysis of surgical treatment modalities for a popliteal pterygium: a meta-analysis

Martin Aman  1 , Maiwand Sidiq  1   2 , Anna Pennekamp  1   3 , Leila Harhaus  1   4 , Mirjam Thielen  5
Affiliations
Meta-Analysis

Comparative analysis of surgical treatment modalities for a popliteal pterygium: a meta-analysis

Martin Aman et al. Arch Orthop Trauma Surg. 2024 May.

Abstract

Introduction: Popliteal pterygium syndrome is a rare congenital disorder characterized by orofacial, cutaneous, musculoskeletal, and genital anomalies. The popliteal pterygium (PP) affects ambulation due to severe knee flexion contracture and equinovarus deformities. Surgical treatment aims to correct these deformities while preserving limb sensibility. However, due to its rarity, surgical guidelines are lacking.

Materials and methods: A meta-analysis according to PRISMA guidelines was conducted to summarize and compare surgical methods for PP. 183 paper were identified in PubMed and data from 32 articles were analyzed, including patient demographics, treatment modalities (Ilizarov fixator, femoral osteotomy, skin/soft tissue procedures, hamstring release, nerve surgery, and amputation), pre- and post-operative abilities to walk, knee joint parameters, complications, and recurrent contractions.

Results: Among 58 patients (87 limbs), Ilizarov fixator demonstrated improved knee and ankle mobility postoperatively, but showed a relatively high surgical session count and complication rates. Femoral osteotomy achieved successful knee posture correction with fewer sessions and no complications. Isolated skin/soft tissue procedures improved flexion contracture and mobility, though they required several procedures. Hamstring release achieved notable contracture reduction but also necessitated multiple interventions. Nerve surgery and amputation had limited data, warranting further investigation.

Conclusion: The management of PP demands a comprehensive approach, considering individual patient characteristics and treatment outcomes. While different surgical modalities offer distinct benefits, a classification or guideline to treat this deformity is still lacking. Further research is essential to validate findings, refine treatment approaches, and enhance the quality of life for individuals with PP.

Keywords: Knee flexion contracture; Meta-analysis; Popliteal pterygium; Popliteal webbing.

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References

    1. Addison A, Webb PJ (1983) Flexion contractures of the knee associated with popliteal webbing. J Pediatr Orthop 3(3):376–379 - DOI - PubMed
    1. Al Kaissi A, Kenis V, Laptiev S, Ghachem MB, Klaushofer K, Ganger R, Grill F (2013) Is webbing (pterygia) a constant feature in patients with Escobar syndrome? Orthop Surg 5(4):297–301 - DOI - PubMed - PMC
    1. Aslan Y, Erduran E, Kutlu N (2000) Autosomal recessive multiple pterygium syndrome: a new variant? Am J Med Genet 93(3):194–197 - DOI - PubMed
    1. Barutçu A, Midoğlu H, Köstem L, Sezgin I (1990) A case with popliteal pterygium syndrome and its surgical treatment. Eur J Plast Surg 13(4):182–184 - DOI
    1. Bennun RD, Stefano E, Moggi LE (2018) Van Der Woude and Popliteal Pterygium syndromes. J Craniofac Surg 29(6):1434–1436 - DOI - PubMed

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