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Randomized Controlled Trial
. 2024 Aug;32(8):1001-1012.
doi: 10.1016/j.joca.2024.04.003. Epub 2024 Apr 12.

Assessing the efficacy of the Stop OsteoARthritis (SOAR) program: A randomized delayed-controlled trial in persons at increased risk of early onset post-traumatic knee osteoarthritis

Justin M Losciale  1 , Linda K Truong  1 , Kexin Zhang  2 , Trish Silvester-Lee  3 , Maxi Miciak  4 , Andrea Pajkic  4 , Christina Y Le  5 , Hui Xie  6 , Alison M Hoens  1 , Amber D Mosewich  7 , Michael A Hunt  8 , Linda C Li  1 , Ewa M Roos  9 , Jackie L Whittaker  10
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Free article
Randomized Controlled Trial

Assessing the efficacy of the Stop OsteoARthritis (SOAR) program: A randomized delayed-controlled trial in persons at increased risk of early onset post-traumatic knee osteoarthritis

Justin M Losciale et al. Osteoarthritis Cartilage. 2024 Aug.
Free article

Abstract

Objective: Assess the efficacy of an 8-week virtual, physiotherapist (PT)-guided knee health program (Stop OsteoARthritis (SOAR)) to improve knee extensor strength in individuals at risk of post-traumatic knee osteoarthritis (PTOA).

Method: In this superiority, randomized delayed-control trial, persons aged 16-35 years, 1-4 years after a self-reported knee joint injury were randomly assigned (1:1) to receive the SOAR program immediately (experimental group) or after a 9-week delay (control group). SOAR includes 1) one-time Knee Camp (virtual PT-guided group education, knee assessment, 1:1 exercise and physical activity (PA) goal-setting); 2) Weekly personalized home-based exercise and PA program with tracking; 3) Weekly 1:1 PT counseling (virtual). The primary outcome was a change in isokinetic knee extensor strength (baseline to 9-weeks). Additional outcomes included change in self-reported knee-related quality-of-life (QOL), self-efficacy, self-management and kinesiophobia, and PA (accelerometer) at 9 and 18-weeks. Linear regression models estimated the effect of the 8-week intervention at the primary endpoint (9-week).

Results: 49 of 54 randomized participants completed the study (91%). Participants were a mean ± standard deviation age of 27 ± 5.0 years, and 2.4 ± 0.9 years post-injury. No mean between group differences for the primary (0.05; 95% confidence interval (CI): -0.10, 0.19) or other outcomes were seen at 9 weeks except for greater improvements in perceived self-management (Partner in Health Scale; 11.3/96, 95%CI: 5.5, 17.1) and kinesiophobia (Tampa Scale of Kinesiophobia; -4.4/33, 95%CI: -7.0, -1.8).

Conclusion: For active persons with elevated risk of PTOA, an 8-week SOAR program did not change knee-related strength, QOL, self-efficacy, or PA, on average, but may benefit the ability to self-manage knee health and kinesiophobia.

Keywords: Anterior cruciate ligament tear; Knee extension strength; Personalized care.

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Conflict of interest statement

Conflicts of Interest ER is on the Editorial Board of Osteoarthritis and Cartilage, the copyright holder of Knee injury and Osteoarthritis Outcome Score (KOOS) and several other patient-reported outcome measures, and co-founder of the Good Life with Osteoarthritis in Denmark (GLA:D), a not-for-profit initiative to implement clinical guidelines in primary care hosted by the University of Southern Denmark. All other authors declare no competing interests. The study funder(s) were not involved in the conduct and reporting of this trial.

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