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Editorial
. 2024 Mar 21;30(11):1470-1474.
doi: 10.3748/wjg.v30.i11.1470.

MicroRNAs in hepatocellular carcinoma treatment: Charting the path forward

Hong T Lin  1 , Antonio F Alvarez Castaneda  1 , Somashekar G Krishna  1 , Khalid Mumtaz  2
Affiliations
Editorial

MicroRNAs in hepatocellular carcinoma treatment: Charting the path forward

Hong T Lin et al. World J Gastroenterol. .

Abstract

MicroRNAs (miRNAs) are recognized for their involvement in the regulation of gene expression and exhibit significant potential in both the prognostic assessment and treatment of hepatocellular carcinoma (HCC). HCC, like other tumors, seldom occurs in isolation; instead, it evolves within a microenvironment featuring oncogenic and tumor-suppressive elements. When combined with suitable delivery vehicles, miRNA technology provides the capability to directly engage with these elements, thereby hindering tumor formation and progression. Ongoing research in this domain holds the promise of enabling a more efficacious and multi-modal treatment approach for HCC in the near future.

Keywords: Exosome; Hepatocellular carcinoma; Mesenchymal stem cell; MicroRNA; Tumor microenvironment.

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Conflict of interest statement

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

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