Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2024 Apr 3;13(2):321-324.
doi: 10.21037/hbsn-23-669. Epub 2024 Mar 27.

Treatment of portal vein thrombosis in cirrhosis with anticoagulation-more than meets the eye?

Ton Lisman  1
Affiliations
Editorial

Treatment of portal vein thrombosis in cirrhosis with anticoagulation-more than meets the eye?

Ton Lisman. Hepatobiliary Surg Nutr. .
No abstract available

Keywords: Portal vein thrombosis (PVT); anticoagulation; cirrhosis; fibrin.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The author has completed the ICMJE uniform disclosure form (available at https://hbsn.amegroups.com/article/view/10.21037/hbsn-23-669/coif). The author has no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Pathogenesis of portal vein thrombosis. The portal vein wall develops intimal thickening in patients with cirrhosis, whereas no intima is present in a healthy portal vein wall. In patients with portal vein thrombosis, the intima thickening has progressed and may be accompanied by a fibrin-rich thrombus within the portal vein lumen. Reprinted with permission from Lisman (9), Hemasphere 2023;7:e886. PVT, portal vein thrombosis.
See this image and copyright information in PMC

Comment on

References

    1. Faccia M, Ainora ME, Ponziani FR, et al. Portal vein thrombosis in cirrhosis: Why a well-known complication is still matter of debate. World J Gastroenterol 2019;25:4437-51. 10.3748/wjg.v25.i31.4437 - DOI - PMC - PubMed
    1. Northup PG, Garcia-Pagan JC, Garcia-Tsao G, et al. Vascular Liver Disorders, Portal Vein Thrombosis, and Procedural Bleeding in Patients With Liver Disease: 2020 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology 2021;73:366-413. 10.1002/hep.31646 - DOI - PubMed
    1. Guerrero A, Campo LD, Piscaglia F, et al. Anticoagulation improves survival in patients with cirrhosis and portal vein thrombosis: The IMPORTAL competing-risk meta-analysis. J Hepatol 2023;79:69-78. 10.1016/j.jhep.2023.02.023 - DOI - PubMed
    1. Loffredo L, Pastori D, Farcomeni A, et al. Effects of Anticoagulants in Patients With Cirrhosis and Portal Vein Thrombosis: A Systematic Review and Meta-analysis. Gastroenterology 2017;153:480-487.e1. 10.1053/j.gastro.2017.04.042 - DOI - PubMed
    1. Turon F, Driever EG, Baiges A, et al. Predicting portal thrombosis in cirrhosis: A prospective study of clinical, ultrasonographic and hemostatic factors. J Hepatol 2021;75:1367-76. 10.1016/j.jhep.2021.07.020 - DOI - PubMed