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Review
. 2024 Sep;39(9):1435-1445.
doi: 10.1002/mds.29794. Epub 2024 Apr 15.

Recommendations for the Management of Initial and Refractory Pediatric Status Dystonicus

Lindsey M Vogt  1 , Kathryn Yang  1   2 , Gabriel Tse  3 , Vicente Quiroz  2 , Zainab Zaman  2 , Laura Wang  1 , Rasha Srouji  2 , Amy Tam  2 , Elicia Estrella  2 , Shannon Manzi  4 , Alfonso Fasano  5   6 , Weston T Northam  7 , Scellig Stone  7 , Mahendranath Moharir  1 , Hernan Gonorazky  1 , Brian McAlvin  8 , Monica Kleinman  8 , Kerri L LaRovere  9 , Carolina Gorodetsky  1   5 , Darius Ebrahimi-Fakhari  2   9
Affiliations
Review

Recommendations for the Management of Initial and Refractory Pediatric Status Dystonicus

Lindsey M Vogt et al. Mov Disord. 2024 Sep.

Abstract

Status dystonicus is the most severe form of dystonia with life-threatening complications if not treated promptly. We present consensus recommendations for the initial management of acutely worsening dystonia (including pre-status dystonicus and status dystonicus), as well as refractory status dystonicus in children. This guideline provides a stepwise approach to assessment, triage, interdisciplinary treatment, and monitoring of status dystonicus. The clinical pathways aim to: (1) facilitate timely recognition/triage of worsening dystonia, (2) standardize supportive and dystonia-directed therapies, (3) provide structure for interdisciplinary cooperation, (4) integrate advances in genomics and neuromodulation, (5) enable multicenter quality improvement and research, and (6) improve outcomes. © 2024 International Parkinson and Movement Disorder Society.

Keywords: childhood‐onset movement disorders; clinical pathway; deep brain stimulation; dystonia; status dystonicus.

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References

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