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Case Reports
. 2023 Jun 25:100138.
doi: 10.1016/j.psycr.2023.100138. Online ahead of print.

Acute Onset of Mania and Psychosis in the Context of Long-COVID: A Case Study

Affiliations
Case Reports

Acute Onset of Mania and Psychosis in the Context of Long-COVID: A Case Study

Orme W et al. Psychiatry Res Case Rep. .

Abstract

Acute phase COVID-19 has been associated with an increased risk for several mental health conditions, but less is known about the interaction of long COVID and mental illness. Prior reports have linked long COVID to PTSD, depression, anxiety, obsessive compulsive symptoms, and insomnia. This case report describes a novel presentation of mania arising in the context of long COVID symptoms with attention given to possible interacting etiological pathways. The case report also highlights the need for integrated, multidisciplinary treatment to support patients whose alarming, confusing, and multidetermined symptoms increase risk of psychological deterioration.

Keywords: Long COVID; bipolar disorder; complex comorbidities; integrated care; mania; personalized medicine.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Figure 1
Figure 1
Detailed timeline of patient's illness course and treatment.

References

    1. Akiskal H.S., Mallya G. Criteria for the “soft” bipolar spectrum: treatment implications. Psychopharmacol Bull. 1987;23:68–73. - PubMed
    1. Albin R.L., Albers J.W., Greenberg H.S., Townsend J.B., Lynn R.B., Burke J.M., Alessi A.G. Acute sensory neuropathy-neuronopathy from pyridoxine overdose. Neurology. 1987;37:1729–1732. doi: 10.1212/wnl.37.11.1729. - DOI - PubMed
    1. Baldessarini R.J., Vázquez G., Tondo L. Treatment of cyclothymic disorder. Commentary. Psychother Psychosom. 2011 doi: 10.1159/000322234. - DOI - PubMed
    1. Broersen L.H.A., Pereira A.M., Jørgensen J.O.L., Dekkers O.M. Adrenal insufficiency in corticosteroids use: Systematic review and meta-analysis. Journal of Clinical Endocrinology and Metabolism. 2015;100:2171–2180. doi: 10.1210/jc.2015-1218. - DOI - PubMed
    1. Correa-Palacio A.F., Hernandez-Huerta D., Gómez-Arnau J., Loeck C., Caballero I. Affective psychosis after COVID-19 infection in a previously healthy patient: a case report. Psychiatry Res. 2020;290 doi: 10.1016/j.psychres.2020.113115. - DOI - PMC - PubMed

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