Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1985 Aug;60(2):137-45.
doi: 10.1016/0030-4220(85)90281-6.

Evaluation of methylprednisolone and flurbiprofen for inhibition of the postoperative inflammatory response

A L Sisk, G J Bonnington
Clinical Trial

Evaluation of methylprednisolone and flurbiprofen for inhibition of the postoperative inflammatory response

A L Sisk et al. Oral Surg Oral Med Oral Pathol. 1985 Aug.

Abstract

The ideal anti-inflammatory agent for use in third molar surgery should control pain, reduce swelling and trismus, and have no unwanted side effects. This investigation evaluated and compared the efficacy of corticosteroids, nonsteroidal anti-inflammatory agents, and placebo for reduction of the acute postoperative inflammatory response and its undesirable sequelae in patients undergoing the surgical removal of impacted third molars. Corticosteroids appeared to have maximal effect in controlling edema but had minimal analgesic effects. Nonsteroidal anti-inflammatory agents appear to be effective analgesics. A combination of these agents may be necessary to control the sequelae of oral surgical procedures most effectively.

PubMed Disclaimer