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Review

New Drugs VII

No authors listed
Tom Perry
, editors.
In: Therapeutics Letter. Vancouver (BC): Therapeutics Initiative; 1994. Letter 44.
2002 May.
Free Books & Documents
Review

New Drugs VII

No authors listed.
Free Books & Documents

Excerpt

Therapeutics Letter 44 reviews four newer drugs: mirtazapine, salmon-calcitonin nasal spray, gatifloxacin, and moxifloxacin. Mirtazapine has no proven efficacy or safety advantage over other antidepressant therapies. It has a prominent sedative effect and patients should be warned that it may cause mental or motor impairment. Salmon-calcitonin nasal spray reduces radiographically-detected new vertebral collapse in patients with at least one vertebral collapse and low BMD (ARR 8.3%), but has no effect on non-vertebral fractures. Long term compliance is poor, even in a trial setting. Gatifloxacin and moxifloxacin have no proven clinical advantages over other fluroquinolones, macrolides or amoxicillin. Based on cost they are not first choice drugs for their approved indications.

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References

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