Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 May;42(2):215-235.
doi: 10.1016/j.ccl.2024.02.008.

Intermediate-Risk and High-Risk Pulmonary Embolism: Recognition and Management: Cardiology Clinics: Cardiac Emergencies

Drew A Birrenkott  1 , Christopher Kabrhel  1 , David M Dudzinski  2
Affiliations
Review

Intermediate-Risk and High-Risk Pulmonary Embolism: Recognition and Management: Cardiology Clinics: Cardiac Emergencies

Drew A Birrenkott et al. Cardiol Clin. 2024 May.

Abstract

Pulmonary embolism (PE) is the third most common cause of cardiovascular death. Every specialty of medical practitioner will encounter PE in their patients, and should be prepared to employ contemporary strategies for diagnosis and initial risk-stratification. Treatment of PE is based on risk-stratification, with anticoagulation for all patients, and advanced modalities including systemic thrombolysis, catheter-directed therapies, and mechanical circulatory supports utilized in a manner paralleling PE severity and clinical context.

Keywords: Catheter-directed therapy; Pulmonary embolism; Pulmonary embolism response team (PERT); Risk stratification; Thrombolysis.

PubMed Disclaimer

Conflict of interest statement

Disclosure Dr. Drew Birrenkott has no disclosures. Dr. Dudzinski has no disclosures. Dr. Kabrhel reports Grants (paid to my institution): Grifols, Diagnostica Stago Consulting/Advisory Boards: Siemens, BMS/Pfizer, Abbot Equity: Insera Therapeutics.

References

    1. Coon WW, Willis PW. Deep venous thrombosis and pulmonary embolism: prediction, prevention and treatment. Am J Cardiol 1959;4:611–21. - PubMed
    1. Goldhaber SZ, Bounameaux H. Pulmonary embolism and deep vein thrombosis. Lancet 2012;379(9828):1835–46. - PubMed
    1. Raskob GE, Angchaisuksiri P, Blanco AN, et al. Thrombosis: a major contributor to global disease burden. Arterioscler Thromb Vasc Biol 2014;34(11):2363–71. - PubMed
    1. Tagalakis V, Patenaude V, Kahn SR, Suissa S. Incidence of and mortality from venous thromboembolism in a real-world population: the Q-VTE Study Cohort. Am J Med 2013;126(9):832.e13–21. - PubMed
    1. Wendelboe AM, Raskob GE. Global burden of thrombosis: Epidemiologic Aspects. Circ Res 2016;118(9):1340–7. - PubMed