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. 2024 May;58(3):147-149.
doi: 10.1007/s13139-023-00836-z. Epub 2024 Jan 18.

Hepatic Superscan in Medullary Thyroid Carcinoma: A Rare Presentation in [18F]FDG PET/CT

Ahmed Saad Abdlkadir  1 , Dhuha Al-Adhami  1 , Baraa Alsyouf  2 , Raghad Alhouwari  1 , Ula Al-Rasheed  1 , Omar Jaber  3 , Issa Mohamad  4 , Akram Al-Ibraheem  1   5
Affiliations

Hepatic Superscan in Medullary Thyroid Carcinoma: A Rare Presentation in [18F]FDG PET/CT

Ahmed Saad Abdlkadir et al. Nucl Med Mol Imaging. 2024 May.
No abstract available

Keywords: Diagnostic challenge; FDG PET/CT; Hepatic superscan; Medullary thyroid carcinoma; Skip metastasis; Unusual metastases.

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Conflict of interest statement

Conflict of InterestAhmed Saad Abdlkadir, Dhuha Al-Adhami, Baraa Alsyouf, Raghad Alhouwari, Ula Al- Rasheed, Issa Mohamad, and Akram Al-Ibraheem declare no conflict of interest.

Figures

Fig. 1
Fig. 1
a Maximum intensity projection image revealed evidence of hypermetabolic malignant large left thyroid lobe lesion (arrowhead), associated with few hypermetabolic metastatic mediastinal lymphadenopathy (curved arrow), several hypermetabolic bone marrow lesions (asterisks), and hypermetabolic massive hepatomegaly (i.e., hepatic superscan, arrow). b Axial PET/CT images of the neck revealed evidence of a large left thyroid lobe lesion with a maximum standardized uptake value (SUVmax) of 6.3 (arrowheads). c Axial PET/CT images of the thorax revealed evidence of a few hypermetabolic mediastinal lymph nodes (SUVmax up to 5.1; curved arrows). d Coronal PET/CT image demonstrating evidence of hepatic super scan (SUVmax 19.8; arrow) visualized concurrently with the hypermetabolic malignant left thyroid lobe tumor (arrowhead). e Axial PET/CT images demonstrating evidence of several hypermetabolic bone marrow lesions involving the left humeral shaft, S1 vertebra, and right proximal femur (SUVmax up to 8.1; asterisks). f Histopathologic examination of the ultrasound-guided liver biopsy sample revealed evidence of metastatic medullary thyroid carcinoma evidenced by positive expression for chromogranin, thyroid transcription factor-1 (TTF-1), and calcitonin immunostains
See this image and copyright information in PMC

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