Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 Apr 16;12(4):e8736.
doi: 10.1002/ccr3.8736. eCollection 2024 Apr.

Denosumab-induced autoimmune hepatitis: Case report

Jawaher J Alotaibi  1 , Bushra Albuqami  2 , Wadha Alotaibi  2 , Rawan M Al Ghamdi  1 , Mohammed Alaskar  1 , Hadi Kuriry  1 , Nasser Almasri  1
Affiliations
Case Reports

Denosumab-induced autoimmune hepatitis: Case report

Jawaher J Alotaibi et al. Clin Case Rep. .

Abstract

This report described a patient not known to have a hepatic disease, found to have a drug-induced autoimmune hepatitis from denosumab. This is an unreported side effect, and here, we presented the possible predisposing factors and suggested monitoring parameters.

Keywords: autoimmune hepatitis; denosumab; drug‐induced hepatitis; hepatitis.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Similar articles

See all similar articles

References

    1. Mieli‐Vergani G, Vergani D, Czaja AJ, et al. Autoimmune hepatitis. Nat Rev Dis Primers. 2018;4(1):18017. doi:10.1038/nrdp.2018.17 - DOI - PubMed
    1. Castiella A, Zapata E, Lucena MI, Andrade RJ. Drug‐induced autoimmune liver disease: a diagnostic dilemma of an increasingly reported disease. World J Hepatol. 2014;6(4):160‐168. doi:10.4254/wjh.v6.i4.160 - DOI - PMC - PubMed
    1. Mack CL, Adams D, Assis DN, et al. Diagnosis and management of Autoimmune hepatitis in adults and children: 2019 practice guidance and guidelines from the American Association for the Study of Liver Diseases. Hepatology. 2020;72(2):671‐722. doi:10.1002/hep.31065 - DOI - PubMed
    1. Oo YH, Hubscher SG, Adams DH. Autoimmune hepatitis: new paradigms in the pathogenesis, diagnosis, and management. Hepatol Int. 2010;4(2):475‐493. doi:10.1007/s12072-010-9183-5 - DOI - PMC - PubMed
    1. Dalekos GN, Samakidou A, Lyberopoulou A, Banakou E, Gatselis NK. Recent advances in the diagnosis and management of autoimmune hepatitis. Pol Arch Intern Med. 2022;132(9). doi:10.20452/pamw.16334 - DOI - PubMed

Publication types

LinkOut - more resources