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. 2024 Apr;6(2):e230216.
doi: 10.1148/ryct.230216.

Cardiac MRI after Sudden Cardiac Arrest: A Systematic Review

Bernhard Scharinger #  1 , Elke Boxhammer #  1 , Richard Rezar  1 , Stefan Hecht  1 , Sarah Wernly  1 , Tobias Widhalm  1 , Michael Lichtenauer  1 , Uta C Hoppe  1 , Klaus Hergan  1 , Bernhard Wernly  1 , Bernhard Strohmer  1 , Reinhard Kaufmann  1
Affiliations

Cardiac MRI after Sudden Cardiac Arrest: A Systematic Review

Bernhard Scharinger et al. Radiol Cardiothorac Imaging. 2024 Apr.

Abstract

Purpose To perform a systematic review to assess the diagnostic and prognostic value of cardiac MRI after sudden cardiac arrest (SCA). Materials and Methods PubMed and Cochrane Library databases were systematically searched for studies investigating cardiac MRI after SCA in adult patients (≥18 years of age). The time frame of the encompassed studies spans from January 2012 to January 2023. The study protocol was preregistered in OSF Registries (www.osf.io/nxaev), and the systematic review was performed following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The quality of the included studies was evaluated using the Newcastle-Ottawa quality assessment scale. Results Fourteen studies involving 1367 individuals, 1257 (91.9%) of whom underwent cardiac MRI, were included. Inconsistent findings were reported on the diagnostic value of cardiac MRI-specific findings. The included studies demonstrated the following main findings: (a) cardiac MRI led to a new or alternative diagnosis in patients with SCA; (b) cardiac MRI identified pathologic or arrhythmogenic substrates; (c) cardiac MRI helped detect myocardial edema (potentially reversible); (d) cardiac MRI provided evidence for the occurrence of adverse events; and (e) functional markers or ventricular dimensions were considered prognostically relevant in a few studies. Relevant challenges in this systematic review were the lack of comparators and reference standards relative to cardiac MRI as the index test and patient selection bias. Conclusion Cardiac MRI following SCA can contribute to the diagnostic process and offer supplementary information essential for treatment planning. Limitations of the review include studies with insufficient comparators and potential bias in patient selection. Systematic review registration link: osf.io/nxaev Keywords: Cardiac MRI, Cardiovascular Disease, Cardiomyopathy, Ischemia, Myocardial Edema, Sudden Cardiac Arrest © RSNA, 2024.

Keywords: Cardiac MRI; Cardiomyopathy; Cardiovascular Disease; Ischemia; Myocardial Edema; Sudden Cardiac Arrest.

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Conflict of interest statement

Disclosures of conflicts of interest: B. Scharinger No relevant relationships. E.B. No relevant relationships. R.R. No relevant relationships. S.H. No relevant relationships. S.W. No relevant relationships. T.W. No relevant relationships. M.L. Lecture payments from Bayer, Novo Nordisk, Novartis, and Boehringer Ingelheim; meeting and/or travel support from Bayer and Pfizer. U.C.H. No relevant relationships. K.H. No relevant relationships. B.W. No relevant relationships. B. Strohmer No relevant relationships. R.K. No relevant relationships.

Figures

Flow diagram shows the identification of studies according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. * = PubMed and Cochrane Library, ** = after abstracts were read.
Flow diagram shows the identification of studies according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. * = PubMed and Cochrane Library, ** = after abstracts were read.
See this image and copyright information in PMC

References

    1. Tamis-Holland JE , Jneid H , Reynolds HR , et al. . Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association . Circulation 2019. ; 139 ( 18 ): e891 – e908 . - PubMed
    1. Rabbat MG , Kwong RY , Heitner JF , et al. . The Future of Cardiac Magnetic Resonance Clinical Trials . JACC Cardiovasc Imaging 2021. ; 15 : 2127 – 2138 . - PubMed
    1. European Heart Rhythm Association; Heart Rhythm Society ; Zipes DP , et al. . ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death) . J Am Coll Cardiol 2006. ; 48 ( 5 ): e247 – e346 . - PubMed
    1. Al-Khatib SM , Stevenson WG , Ackerman MJ , et al. . 2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: Executive summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society . Heart Rhythm 2018. ; 15 ( 10 ): e190 – e252 . [Published correction appears in Heart Rhythm 2018;15(11):e278–e281.] - PubMed
    1. Hayashi M , Shimizu W , Albert CM . The spectrum of epidemiology underlying sudden cardiac death . Circ Res 2015. ; 116 ( 12 ): 1887 – 1906 . - PMC - PubMed

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