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Practice Guideline
. 2024 Sep;66(9):1133-1147.
doi: 10.1111/dmcn.15921. Epub 2024 Apr 19.

Pharmacological and neurosurgical management of cerebral palsy and dystonia: Clinical practice guideline update

Darcy Fehlings  1 , Brenda Agnew  2 , Hortensia Gimeno  3 , Adrienne Harvey  4 , Kate Himmelmann  5 , Jean-Pierre Lin  6 , Jonathan W Mink  7 , Elegast Monbaliu  8 , James Rice  9 , Emma Bohn  1 , Yngve Falck-Ytter  10
Affiliations
Practice Guideline

Pharmacological and neurosurgical management of cerebral palsy and dystonia: Clinical practice guideline update

Darcy Fehlings et al. Dev Med Child Neurol. 2024 Sep.

Abstract

Dystonia, typically characterized by slow repetitive involuntary movements, stiff abnormal postures, and hypertonia, is common among individuals with cerebral palsy (CP). Dystonia can interfere with activities and have considerable impact on motor function, pain/comfort, and ease of caregiving. Although pharmacological and neurosurgical approaches are used clinically in individuals with CP and dystonia that is causing interference, evidence to support these options is limited. This clinical practice guideline update comprises 10 evidence-based recommendations on the use of pharmacological and neurosurgical interventions for individuals with CP and dystonia causing interference, developed by an international expert panel following the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. The recommendations are intended to help inform clinicians in their use of these management options for individuals with CP and dystonia, and to guide a shared decision-making process in selecting a management approach that is aligned with the individual's and the family's values and preferences.

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FIGURE 1
Interpretation aid for the care pathway.
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References

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