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. 2024 Oct;124(5):1581-1589.
doi: 10.1007/s13760-024-02559-0. Epub 2024 Apr 20.

Intracranial extra-axial chondromas: clues to computed tomography and magnetic resonance imaging diagnosis

Mustafa Kemal Demir  1 , Özlem Yapıcıer  2 , Önder Ertem  3 , Ozge Ecertastan  4 , Deniz Kılıc  3 , Aslan Güzel  5 , Türker Kılıc  3
Affiliations

Intracranial extra-axial chondromas: clues to computed tomography and magnetic resonance imaging diagnosis

Mustafa Kemal Demir et al. Acta Neurol Belg. 2024 Oct.

Abstract

Aim: We aimed to describe the computed tomography (CT) and magnetic resonance (MR) imaging findings of intracranial extra-axial chondroma.

Material and methods: We retrospectively evaluated the imaging findings of CT and MR examinations of six patients (three men and three women, aged 21-66 years) with histopathological diagnoses of intracranial extra-axial chondroma.

Results: Four tumors were located in the frontal region and two in the cavernous sinus. All the tumors showed low signals on diffusion-weighted images and high signals on apparent diffusion coefficient maps without restricted diffusion. There was no perifocal edema in all the tumors. Cavernous sinus chondromas were associated with bone erosion and anterior displacement of the internal carotid arteries, but without calcification. Calcification was present in all frontal chondromas. All the tumors revealed low signals on T1-weighted MR images. Frontal chondromas revealed mixed signals, but cavernous sinus chondromas were brightly hyperintense on T2-weighted MR images. No enhancement was detected in the two chondromas. An intense homogeneous enhancement was detected in a cavernous sinus chondroma.

Conclusion: The imaging appearances of frontal extra-axial chondromas and cavernous sinus chondromas may have different imaging appearances. Although there is a wide range of imaging findings, the absence of restricted diffusion, perifocal edema, enhancement, and presence of low signals on T1-weighted MR images in a well-circumscribed calcified extra-axial mass should suggest an intracranial chondroma.

Keywords: Chondroma; Computed tomography; Extra-axial; Intracranial; Magnetic resonance imaging.

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Conflict of interest statement

Declarations. Conflict of interests: The authors declare no conflict of interest. Ethical approval: This article does not contain any studies with human participants or animals performed by any of the authors. Informed consent: Informed consent was obtained from the patients included in the study.

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