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Review
. 2024 Mar;38(1):101944.
doi: 10.1016/j.berh.2024.101944. Epub 2024 Apr 21.

Myofascial pain - A major player in musculoskeletal pain

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Free article
Review

Myofascial pain - A major player in musculoskeletal pain

Christopher Lam et al. Best Pract Res Clin Rheumatol. 2024 Mar.
Free article

Abstract

Myofascial pain is a soft tissue pain syndrome with local and referred musculoskeletal pain arising from trigger points. Myofascial pain and myofascial pain syndromes are among some of the most common acute and chronic pain conditions. Myofascial pain can exist independently of other pain generators or can coexist with or is secondary to other acute and chronic painful musculoskeletal conditions. Myofascial pain is most effectively treated with a multimodal treatment plan including injection therapy (known as trigger point injections, physical therapy, postural or ergonomic correction, and treatment of underlying musculoskeletal pain generators. The objectives of this review are to outline the prevalence of myofascial pain, describe the known pathophysiology of myofascial pain and trigger points, discuss the clinical presentation of myofascial pain, and present evidence-based best practices for pharmacologic, non-pharmacologic, and interventional treatments for myofascial pain.

Keywords: Botulinum toxin; Corticosteroid; Local anesthetic; Myofascial pain; Piriformis syndrome; Trigger point injection.

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Conflict of interest statement

Declaration of competing interest ALC has received consulting fees from Swing Therapeutics and Scilex Pharmaceuticals.

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