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Review
. 2024 Apr 20;16(4):e58667.
doi: 10.7759/cureus.58667. eCollection 2024 Apr.

The Interplay Between Diabetes and Oral Health: A Comprehensive Bibliometric Analysis of Clinical Trials (1967-2024)

Namrata Dagli  1 , Mainul Haque  1   2 , Santosh Kumar  3
Affiliations
Review

The Interplay Between Diabetes and Oral Health: A Comprehensive Bibliometric Analysis of Clinical Trials (1967-2024)

Namrata Dagli et al. Cureus. .

Abstract

Recognizing the complex interaction between diabetes and oral health is crucial, considering the increasing worldwide prevalence of these conditions. This bibliometric analysis delves into the extensive body of literature concerning the impact of diabetes on oral health, utilizing data retrieved from PubMed. The publishing trends indicate a growing research interest in the field over time, with notable peaks and declines. Coauthorship analyses of authors and institutions illuminated collaborative networks within the research community. Two departments at Ahvaz Jundishapur University of Medical Sciences in Iran, namely the Department of Periodontology within the School of Dentistry and the Diabetes Research Center within the Health Research Institute, demonstrated the highest total link strength. The co-occurrence analysis of keywords also unveiled thematic clusters, reflecting research focus areas and evolving trends. The analysis of topic trends highlighted persistent research interests in topics, such as type 2 diabetes mellitus, glycated hemoglobin, periodontitis, and therapy for chronic periodontitis, with shifts in therapeutic modalities investigated. The thematic map suggests that dental implants and tumor necrosis factor-alpha are emerging terms in the field that have gained more traction recently. Furthermore, the analysis of scientific production by country indicated varied contributions, with Brazil leading in publication output. Analysis of collaboration among corresponding authors' countries identified Italy exhibiting substantial international collaboration, while most of the countries primarily produced single-country publications. This comprehensive analysis provides insights into the multifaceted landscape of research on diabetes and oral health, emphasizing ongoing efforts to understand and address the complex interplay between these conditions.

Keywords: bibliometric review; chronic metabolic disorder; chronic periodontitis; diabetes mellitus; glycated hemoglobin; network visualization; oral health; overlay visualization; periodontal therapy; scientometric analysis.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Process of selection of studies.
Figure 2
Figure 2. Annual scientific production analysis of clinical trials on the impact of diabetes on oral health.
The image is created by the author (Namrata Dagli) of this study.
Figure 3
Figure 3. Most relevant authors based on the number of published clinical trials on the impact of diabetes on oral health.
The image is created by the author (Namrata Dagli) of this study.
Figure 4
Figure 4. Overlay visualization of the coauthorship analysis of authors.
Weight = total link strength values, scores = average publication year, threshold of published clinical trials = 2. The size of the nodes is directly proportional to the total link strength values. The image is created by the author (Namrata Dagli) of this study by using VOSviewer (Leiden, Netherlands: Leiden University).
Figure 5
Figure 5. An overlay visualization of the most extensive set of connected items found in the authors' coauthorship analysis.
Weight = total link strength values. Each node represents an author, and the connection between nodes represents coauthorship relationships. The image is created by the author (Namrata Dagli) of this study by using VOSviewer (Leiden, Netherlands: Leiden University).
Figure 6
Figure 6. Network visualization of coauthorship analysis of the most extensive set of connected institutions.
Weight = total link strength values. Each node represents an institution. Cluster 1 is red, cluster 2 is green, cluster 3 is blue, and cluster 4 is yellow. The image is created by the author (Namrata Dagli) of this study by using VOSviewer (Leiden, Netherlands: Leiden University).
Figure 7
Figure 7. Overlay visualization of cooccurrence analysis of keywords.
The image is created by the author (Namrata Dagli) of this study by using VOSviewer (Leiden, Netherlands: Leiden University).
Figure 8
Figure 8. Analysis of topic trends in clinical trials in PubMed on the impact of diabetes on oral health.
The image is created by the author (Namrata Dagli) of this study.
Figure 9
Figure 9. Thematic evolution analysis of keywords used in clinical trials on the impact of diabetes on oral health.
The image is created by the author (Namrata Dagli) of this study by using the Biblioshiny App (Naples, Italy: Aria and Cuccurullo).
Figure 10
Figure 10. Thematic map (minimum frequency occurrence of keywords per thousand documents=25).
The image is created by the author (Namrata Dagli) of this study by using the Biblioshiny App (Naples, Italy: Aria and Cuccurullo).
Figure 11
Figure 11. Scientific production of countries.
The image is created by the author (Namrata Dagli) of this study.
Figure 12
Figure 12. Analysis of countries of corresponding authors.
The image is created by the author (Namrata Dagli) of this study.
Figure 13
Figure 13. Key findings of bibliometric analysis on the impact of diabetes on oral health.
The image is created by the author (Namrata Dagli) of this study using the premium version of BioRender (ON, Canada: Science Suite Inc.).
See this image and copyright information in PMC

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