Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Jul 4;144(1):113-117.
doi: 10.1182/blood.2024024048.

Testing for t(3;8) in MYC/BCL6-rearranged large B-cell lymphoma identifies a high-risk subgroup with inferior survival

Bernard D Maybury  1 , Lisa James  2 , Neil Phillips  3 , Indrani Venkatadasari  4 , Iman Qureshi  5 , James Riley  1 , Georgina Talbot  3 , Shivir Moosai  6   7 , Hannah Giles  3 , Nicola Chadderton  2 , James Dowds  2 , Pallav Rakesh  8 , Henry Crosland  1 , Aidan Haslam  1 , Sarah Lane  9 , Monica Vega Gonzalez  10 , David Davies  6 , George Cherian  9 , Amir Shenouda  8 , Praveen Kaudlay  4 , Jane Starczynski  2 , Zbigniew Rudzki  2 , Sridhar Chaganti  1
Affiliations
Free article

Testing for t(3;8) in MYC/BCL6-rearranged large B-cell lymphoma identifies a high-risk subgroup with inferior survival

Bernard D Maybury et al. Blood. .
Free article

Abstract

A reciprocal t(3;8) BCL6::MYC fusion is common in large B-cell lymphoma (LBCL) with MYC and BCL6 disruption. These pseudo-double-hit cases are not adverse, whereas t(3;8)-MYC/BCL6 lymphoma has an inferior prognosis relative to other MYC-rearranged LBCL.

PubMed Disclaimer

References

Substances

LinkOut - more resources