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Editorial
. 2024 Jun;25(3):177-178.
doi: 10.1038/s41435-024-00273-8. Epub 2024 Apr 22.

Oxidized phospholipids during microbial challenge: friend or foe?

Henrique G Colaço  1   2 , Kelsey Voss  3
Affiliations
Editorial

Oxidized phospholipids during microbial challenge: friend or foe?

Henrique G Colaço et al. Genes Immun. 2024 Jun.
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Oxidized phospholipids trigger a hyper-inflammatory state during infection.
Infection triggers an accumulation of oxidized phospholipids (oxPLs) in macrophages which bind to AKT and subsequently alter the methylation status of the Il10 gene. This epigenetic silencing of IL-10 production leads to a life-threatening dysregulation in inflammation.
See this image and copyright information in PMC

Comment on

References

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