Unveiling the TRAPP: The role of plant TRAPPII in adaptive growth decisions

Abstract

The regulation of intracellular membrane traffic is coupled with the cell's need to respond to environmental stimuli, which ultimately is critical for different processes such as cell growth and development. In this issue, Wiese et al. (https://www.doi.org/10.1083/jcb.202311125) explore the role of the trans-Golgi network (TGN) in stress response, exposing its role in mediating adaptive growth decisions.

Figure 1.

SKs, such as BIN2, are pivotal in integrating various signaling pathways, responses to extracellular cues. According to Wiese et al. (5), the integration of signals and decision-making processes occurs at the interface between AtSK and TRAPPII. Downstream of TRAPPII, Rab GTPases play a crucial role in executing decisions. The phosphorylation status of AtTRS120 may modulate TRAPPII GEF activity, affecting the function of its cognate Rabs. PM: plasma membrane; P enclosed in green circle: phosphate group; Rab scwitch regions (I [red] and II [green]) are indicated.