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. 2024 Jul;44(7):995-1000.
doi: 10.1038/s41372-024-01955-x. Epub 2024 Apr 23.

Managing established bronchopulmonary dysplasia without using routine blood gas measurements

Matthew J Kielt  1 , Laurie C Eldredge  2 , Edward G Shepherd  1 , Robert J DiGeronimo  2 , Audrey N Miller  1 , Roopali Bapat  1 , George El-Ferzli  1 , Stephen E Welty  2 , Leif D Nelin  3
Affiliations

Managing established bronchopulmonary dysplasia without using routine blood gas measurements

Matthew J Kielt et al. J Perinatol. 2024 Jul.

Abstract

Objective: Routine blood gas measurements are common in infants with severe bronchopulmonary dysplasia (sBPD) and are a noxious stimulus. We developed a guideline-driven approach to evaluate the care of infants with sBPD without routine blood gas sampling in the chronic phase of NICU care (after diagnosis at 36 weeks PMA).

Study design: We examined blood gas utilization and outcomes in our sBPD inpatient care unit using data collected between 2014 and 2020.

Results: 485 sBPD infants met inclusion criteria, and 303 (62%) never had a blood gas obtained after 36 weeks PMA. In infants who had blood gas measurements, the median number of total blood gases per patient was only 4 (IQR 1-10). We did not identify adverse effects on hospital outcomes in patients without routine blood gas measurements.

Conclusions: We found that patients with established BPD could be managed without routine blood gas analyses after 36 weeks PMA.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Flow diagram for the study.
Five hundred and fifty-nine patients were admitted to the BPD NICU between 2015 and 2020 at ≥36 weeks PMA. Of those, 74 met exclusion criteria, leaving 485 that met inclusion criteria. There were 303 patients who never had a blood gas performed after admission to the BPD ICU.
See this image and copyright information in PMC

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