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. 2024 Apr 4;27(6):244.
doi: 10.3892/etm.2024.12532. eCollection 2024 Jun.

An observational study of symmetrical VSD occluder for transcatheter closure of ruptured sinus of Valsalva aneurysm

Wei Chen  1 , Tongbin Li  1 , Xiaolin Lei  1 , Haitao Liu  1
Affiliations

An observational study of symmetrical VSD occluder for transcatheter closure of ruptured sinus of Valsalva aneurysm

Wei Chen et al. Exp Ther Med. .

Abstract

This study evaluated the immediate and 1-year postoperative outcomes of 14 patients with ruptured Valsalva aneurysmal sinus (RSVA) using symmetric ventricular septal defect (VSD) occluder for transcatheter closure (TCC). The sites of rupture were from the non-coronary sinus to the right atrium (RA) in 10 cases (71.4%), the right coronary sinus (RCS) to the RA in 3 cases (21.4%) and the RCS to the right ventricle in 1 case (7.2%). The defects (5-11 mm) were closed with a symmetrical VSD device. During the follow-up (12 months), the enlarged heart of the patients had significantly shrunk and the NYHA improved after closure. In 1 case, a moderate residual shunt was present and the patient suffered from hemolysis at 2 h after the operation, and 1 patient was transferred to surgery for aortic regurgitation 1 year after the initial treatment of RSVA. In conclusion, the TCC of RSVA with the China made symmetrical VSD occluder is safe and effective.

Keywords: rupture of sinus of Valsalva aneurysm; symmetrical closure devices; transcatheter closure.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Operation of the transcatheter closure of the RSVA. (A) Aortic root angiography revealed no coronary sinus aneurysm rupturing into the right atrium. (B) A stable arteriovenous wire loop was established. (C) The RSVA was blocked using a Memory ventricular septal defect occluder delivered via the arteriovenous track. (D) Complete occlusion after device placement. RSVA, ruptured sinus of Valsalva aneurysm.
Figure 2
Figure 2
Transthoracic ultrasound follow-up after transcatheter closure. (A) Preoperative chest echocardiography revealed that the ruptured sinus of Valsalva aneurysm had broken into the non-coronary sinus. (B) TTE revealed a complete closure of the breach 1 month after the operation. (C) TTE revealed a small residual shunt 6 months after the operation. (D) TTE revealed a small residual shunt 12 months after the operation. TTE, transthoracic echocardiography.
Figure 3
Figure 3
Size of cardiac cavities 6 and 12 months after occlusion. The size of the LA (mm), RA (mm) and LV (mm) reduced significantly 6 and 12 months after occlusion. The RV (mm) did not significantly change. *P<0.05; **P<0.01. LA, left atrium; RA, right atrium; LV, left ventricle; RV, right ventricle.
See this image and copyright information in PMC

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