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Case Reports
. 2024 Apr 10:54:102737.
doi: 10.1016/j.eucr.2024.102737. eCollection 2024 May.

A case of extremely rare pathology: Renal malakoplakia

Yassine Daghdagh  1 , Ibtissam Razzouki  2 , Amine Moataz  1 , Nisrine Bennani  2 , Mohamed Dakir  1 , Adil Debbagh  1 , Rachid Aboutaieb  1
Affiliations
Case Reports

A case of extremely rare pathology: Renal malakoplakia

Yassine Daghdagh et al. Urol Case Rep. .

Abstract

Malakoplakia is a granulomatous tissue inflammation with a characteristic histological appearance, mainly affecting the urogenital system and morphologically reflecting a macrophage disease. If bladder involvement is the most common, renal involvement is very rare and may be responsible for a differential diagnosis problem with renal cell carcinoma. We present a clinical case of renal malacoplakia mimicking malignant renal cell carcinoma diagnosed after partial nephrectomy in a 58-year-old woman with no history of recurrent urinary infections.

Keywords: Cell carcinoma; Kidney; Malakoplakia; ‘‘Michaelis-gutman’’bodies.

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Conflict of interest statement

The authors declare any conflict of interest.

Figures

Fig. 1
Fig. 1
CT scan showing right mid renal solidocyst mass, oval, well limited, enhanced heterogeneously after injection of contrast product, measuring 49*41mm.
Fig. 2
Fig. 2
Malakoplakia with sheets of macrophages with granular eosinophilic cytoplasm and neutrophils scattered in the interstitium and tubules, with evidence of Michaelis-Gutmann bodies (yellow arrows) (haematoxylin and eosin staining). NB: We do not have von Kossa staining (calcium).
Fig. 3
Fig. 3
Malakoplakia with sheets of macrophages with granular cytoplasm (haematoxylin and eosin staining).
See this image and copyright information in PMC

References

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    1. Daniela Knights Purnell Stephanie, Davis Bonnie, Burch-Smith Rhonda. Pamela ColemanRenal malakoplakia mimicking a malignant renal carcinoma: a patient case with literature review. BMJ Case Rep. 2015;2015 - PMC - PubMed
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