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. 2024 Apr 22;70(3):e20231082.
doi: 10.1590/1806-9282.20231082. eCollection 2024.

Diagnostic value of transthoracic needle biopsy in lung tumors

Ozlem Sogukpinar  1 , Ulku Aka Akturk  1 , Makbule Ozlem Akbay  1 , Erdal Tatlidil  2 , Dilek Ernam  1
Affiliations

Diagnostic value of transthoracic needle biopsy in lung tumors

Ozlem Sogukpinar et al. Rev Assoc Med Bras (1992). .

Abstract

Objective: Thoracic ultrasonography is widely used in imaging peripheral lesions and invasive interventional procedures. The aim of this study was to assess the diagnostic value of thoracic ultrasonography-guided transthoracic needle aspiration biopsy and the factors affecting the diagnosis of peripheral tumoral lung lesions.

Methods: The lesion size, biopsy needle type, number of blocks, complications, and pathology results were compared in 83 patients between January 2015 and July 2018. The cases with pathological non-diagnosis and definite pathological diagnosis were determined. For the assessment of the factors affecting diagnosis, the size of the lesions and the biopsy needle type were evaluated. Biopsy preparations containing non-diagnostic atypical cells were referred to a cytopathologist. The effect of the cytopathological examination on the diagnosis was also evaluated.

Results: Pathological diagnosis was made in 66.3% of the cases; cell type could not be determined in 22.9% of the cases, and they were referred to a cytopathologist. After the cytopathologist's examination, the diagnosis rate increased to 80.7%. Diagnosis rates were higher when using tru-cut than Chiba and higher in cases with tumor size >2 cm than smaller.

Conclusion: Thoracic ultrasonography-guided transthoracic needle aspiration biopsy is a preferred approach to the diagnosis of peripheral tumoral lung lesions, given its high diagnostic rate, in addition to being cheap, highly suitable for bedside use, and safe, and the lack of radiation exposure.

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Conflict of interest statement

Conflicts of interest: the authors declare there is no conflicts of interest.

References

    1. Zhou Q, Dong J, He J, Liu D, Tian DH, Gao S, et al. The society for translational medicine: indications and methods of percutaneous transthoracic needle biopsy for diagnosis of lung cancer. J Thorac Dis. 2018;10(9):5538–5544. doi: 10.21037/jtd.2018.09.28. - DOI - PMC - PubMed
    1. Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JHM, Beasley MB, et al. The 2015 World Health Organization classification of lung tumors: impact of genetic, clinical and radiologic advances since the 2004 classification. J Thorac Oncol. 2015;10(9):1243–1260. doi: 10.1097/JTO.0000000000000630. - DOI - PubMed
    1. Manhire A, Charig M, Clelland C, Gleeson F, Miller R, Moss H, et al. Guidelines for radiologically guided lung biopsy. Thorax. 2003;58(11):920–936. doi: 10.1136/thorax.58.11.920. - DOI - PMC - PubMed
    1. Nakajima T, Yasufuku K, Fujiwara T, Yoshino I. Recent advances in endobronchial ultrasound-guided transbronchial needle aspiration. Respir Investig. 2016;54(4):230–236. doi: 10.1016/j.resinv.2016.02.002. - DOI - PubMed
    1. Lee MH, Lubner MG, Hinshaw JL, Pickhardt PJ. Ultrasound guidance versus CT Guidance for peripheral lung biopsy: performance according to lesion size and pleural contact. AJR Am J Roentgenol. 2018;210(3):W110–W117. doi: 10.2214/AJR.17.18014. - DOI - PubMed