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. 2024 Apr 24;14(1):9452.
doi: 10.1038/s41598-024-57521-0.

A robust optimization model for multi-objective blood supply chain network considering scenario analysis under uncertainty: a multi-objective approach

Saeed Khakshouri Fariman  1 , Kasra Danesh  2 , Mostafa Pourtalebiyan  3 , Zahra Fakhri  4 , Ali Motallebi  5 , Ali Fozooni  6
Affiliations

A robust optimization model for multi-objective blood supply chain network considering scenario analysis under uncertainty: a multi-objective approach

Saeed Khakshouri Fariman et al. Sci Rep. .

Abstract

Annually, different regions of the world are affected by natural disasters such as floods and earthquakes, resulting in significant loss of lives and financial resources. These events necessitate rescue operations, including the provision and distribution of relief items like food and clothing. One of the most critical challenges in such crises is meeting the blood requirement, as an efficient and reliable blood supply chain is indispensable. The perishable nature of blood precludes the establishment of a reserve stock, making it essential to minimize shortages through effective approaches and designs. In this study, we develop a mathematical programming model to optimize supply chains in post-crisis scenarios using multiple objectives. Presented model allocates blood to various demand facilities based on their quantity and location, considering potential situations. We employ real data from a case study in Iran and a robust optimization approach to address the issue. The study identifies blood donation centers and medical facilities, as well as the number and locations of new facilities needed. We also conduct scenario analysis to enhance the realism of presented approach. Presented research demonstrates that with proper management, crises of this nature can be handled with minimal expense and deficiency.

Keywords: Blood supply chain; Disaster; HealthCare; Robustness.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
The review of framing methods.
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Algorithm 1: Objective 1
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Algorithm 1: Objective 2
Figure 2
Figure 2
Distance between centers of blood from treatment centers (in km).
Figure 3
Figure 3
Distance of temporary facilities from blood centers (in km).
Figure 4
Figure 4
Demand for injured (people) different scenarios.
Figure 5
Figure 5
Demand for injured (people) different scenarios.
Figure 6
Figure 6
Calculation of blood capacity under the first scenario.
Figure 7
Figure 7
Number and location of temporary and permanent facilities to be set up and constructed, Black: Scenario 3, Green: Scenario 2, Red: Scenario 1, Circle is Blood centers, Lines are scenarios.
Figure 8
Figure 8
The amount of blood deficiency at the end of period t under the scenario z (blood unit).
See this image and copyright information in PMC

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References

    1. Jabbarzadeh A, Fahimnia B, Seuring S. Dynamic supply chain network design for the supply of blood in disasters: A robust model with real world application. Transp. Res. Part E: Logist. Transp. Rev. 2014;70:225–244. doi: 10.1016/j.tre.2014.06.003. - DOI
    1. Nollet KE, Ohto H, Yasuda H, Hasegawa A. The great East Japan earthquake of March 11, 2011, from the vantage point of blood banking and transfusion medicine. Transf. Med. Rev. 2013;27(1):29–35. doi: 10.1016/j.tmrv.2012.07.001. - DOI - PubMed
    1. Sha Y, Huang J. The multi-period location-allocation problem of engineering emergency blood supply systems. Syst. Eng. Procedia. 2012;5:21–28. doi: 10.1016/j.sepro.2012.04.004. - DOI
    1. Sasser, S. M. et al. In a moment's notice; surge capacity for terrorist bombings: Challenges and proposed solutions (2007).
    1. Flegel WA. Fresh blood for transfusion: How old is too old for red blood cell units? Blood Transf. 2012;10(3):247. - PMC - PubMed

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