Analysis of laboratory data transmission between two healthcare institutions using a widely used point-to-point health information exchange platform: a case report
- PMID: 38660616
- PMCID: PMC11042873
- DOI: 10.1093/jamiaopen/ooae032
Analysis of laboratory data transmission between two healthcare institutions using a widely used point-to-point health information exchange platform: a case report
Abstract
Objective: The objective was to identify information loss that could affect clinical care in laboratory data transmission between 2 health care institutions via a Health Information Exchange platform.
Materials and methods: Data transmission results of 9 laboratory tests, including LOINC codes, were compared in the following: between sending and receiving electronic health record (EHR) systems, the individual Health Level Seven International (HL7) Version 2 messages across the instrument, laboratory information system, and sending EHR.
Results: Loss of information for similar tests indicated the following potential patient safety issues: (1) consistently missing specimen source; (2) lack of reporting of analytical technique or instrument platform; (3) inconsistent units and reference ranges; (4) discordant LOINC code use; and (5) increased complexity with multiple HL7 versions.
Discussion and conclusions: Using an HIE with standard messaging, SHIELD (Systemic Harmonization and Interoperability Enhancement for Laboratory Data) recommendations, and enhanced EHR functionality to support necessary data elements would yield consistent test identification and result value transmission.
Keywords: clinical laboratory information systems; data quality; health information exchange; health information interoperability; patient safety.
© The Author(s) 2024. Published by Oxford University Press on behalf of the American Medical Informatics Association.
Conflict of interest statement
H.S.L. is a member of the Clinical Advisory Council for Health Gorilla, Inc., with stock options. W.S.C., R.A.C., M.E.E., A.E., A.K., E.D.K., S.H.M., G.T.W., L.W., D.W., and S.P. report no relevant conflicts.
Figures


Similar articles
-
LOINC, a universal standard for identifying laboratory observations: a 5-year update.Clin Chem. 2003 Apr;49(4):624-33. doi: 10.1373/49.4.624. Clin Chem. 2003. PMID: 12651816
-
Investigating the semantic interoperability of laboratory data exchanged using LOINC codes in three large institutions.AMIA Annu Symp Proc. 2011;2011:805-14. Epub 2011 Oct 22. AMIA Annu Symp Proc. 2011. PMID: 22195138 Free PMC article.
-
Semantic interoperability in Czech healthcare environment supported by HL7 version 3.Methods Inf Med. 2010;49(2):186-95. doi: 10.3414/ME09-02-0018. Epub 2009 Nov 20. Methods Inf Med. 2010. PMID: 19936441
-
Logical Observation Identifiers Names and Codes for Laboratorians.Arch Pathol Lab Med. 2020 Feb;144(2):229-239. doi: 10.5858/arpa.2018-0477-RA. Epub 2019 Jun 20. Arch Pathol Lab Med. 2020. PMID: 31219342 Review.
-
In support of interoperability: A laboratory perspective.Int J Lab Hematol. 2023 Aug;45(4):436-441. doi: 10.1111/ijlh.14113. Epub 2023 Jun 20. Int J Lab Hematol. 2023. PMID: 37337695 Review.
Cited by
-
Laboratory Data as a Potential Source of Bias in Healthcare Artificial Intelligence and Machine Learning Models.Ann Lab Med. 2025 Jan 1;45(1):12-21. doi: 10.3343/alm.2024.0323. Epub 2024 Oct 24. Ann Lab Med. 2025. PMID: 39444135 Free PMC article. Review.
References
-
- LOINC ® from Regenstrief. Home. 2021. LOINC®. Accessed August 30, 2023. http://www.LOINC®.org/
-
- SNOMED CT ® starter guide. 2021. SNOMED International. Accessed August 30, 2023. https://confluence.ihtsdotools.org/display/DOCSTART/SNOMED+CT+Starter+Guide
Publication types
LinkOut - more resources
Full Text Sources