HLA antigens in psoriasis and psoriatic arthritis
- PMID: 3866077
- PMCID: PMC1049511
- DOI: 10.1136/jmg.22.6.492
HLA antigens in psoriasis and psoriatic arthritis
Abstract
HLA phenotypes were determined in 50 patients with psoriasis alone and in 50 patients with psoriasis and psoriatic arthritis. Positive associations were found in both groups with B13, B17, B37, Cw6, and DR7, and in addition with C4A6. Higher relative risks were found in respect to the patients with psoriasis alone compared with those with arthritis, and this suggests the involvement of additional genetic factors predisposing to peripheral arthritis. In patients with psoriasis only, the presence of Cw6 was associated with a significantly earlier age of onset.
Similar articles
-
Histocompatibility alloantigens in psoriasis and psoriatic arthritis. Evidence for the influence of multiple genes in the major histocompatibility complex.J Clin Invest. 1980 Oct;66(4):670-5. doi: 10.1172/JCI109903. J Clin Invest. 1980. PMID: 6932404 Free PMC article.
-
Psoriatic arthritis: risk factors for patients with psoriasis - a study based on histocompatibility antigen frequencies.J Rheumatol. 1983 Aug;10(4):633-6. J Rheumatol. 1983. PMID: 6413688
-
Clinical and immunogenetic subsets of psoriatic arthritis.Clin Exp Rheumatol. 1984 Apr-Jun;2(2):105-9. Clin Exp Rheumatol. 1984. PMID: 6598100
-
Human leukocyte antigens as psoriasis inheritance and susceptibility markers.Arch Immunol Ther Exp (Warsz). 2005 Sep-Oct;53(5):428-33. Arch Immunol Ther Exp (Warsz). 2005. PMID: 16314826 Review.
-
Psoriatic arthritis.Clin Rheum Dis. 1985 Apr;11(1):61-85. Clin Rheum Dis. 1985. PMID: 3888505 Review. No abstract available.
Cited by
-
Expanding the Genetic Framework: Insights into Non-HLA-B27 Contributions to Axial Spondylarthritis.Medicina (Kaunas). 2025 Apr 25;61(5):793. doi: 10.3390/medicina61050793. Medicina (Kaunas). 2025. PMID: 40428751 Free PMC article.
-
PERB11 (MIC): a polymorphic MHC gene is expressed in skin and single nucleotide polymorphisms are associated with psoriasis.Clin Exp Immunol. 2000 Mar;119(3):553-8. doi: 10.1046/j.1365-2249.2000.01140.x. Clin Exp Immunol. 2000. PMID: 10691930 Free PMC article.
-
Allelic and haplotypic HLA analysis in patients with psoriatic arthritis: Low frequency of common alleles.Biomedica. 2024 Dec 23;44(Sp. 2):178-190. doi: 10.7705/biomedica.7555. Biomedica. 2024. PMID: 39836838 Free PMC article. English, Spanish.
-
Apremilast Pharmacogenomics in Russian Patients with Moderate-to-Severe and Severe Psoriasis.J Pers Med. 2020 Dec 29;11(1):20. doi: 10.3390/jpm11010020. J Pers Med. 2020. PMID: 33383665 Free PMC article.
-
Autoinflammatory pustular neutrophilic diseases.Dermatol Clin. 2013 Jul;31(3):405-25. doi: 10.1016/j.det.2013.04.001. Epub 2013 Jun 2. Dermatol Clin. 2013. PMID: 23827244 Free PMC article. Review.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials