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Multicenter Study
. 2024 Sep 26;79(3):600-603.
doi: 10.1093/cid/ciae230.

Performance of Urinalysis Parameters in Predicting Urinary Tract Infection: Does One Size Fit All?

Sonali D Advani  1 , Rebecca North  2 , Nicholas A Turner  1 , Sahra Ahmadi  3 , Julia Denniss  4 , Adero Francis  3 , Rachel Johnson  3 , Anum Hasan  5 , Faryal Mirza  5 , Sarah Pardue  5 , Meghana Rao  4 , Yasmin Rosshandler  3 , Helen Tang  4 , Kenneth E Schmader  6 , Deverick J Anderson  1
Affiliations
Multicenter Study

Performance of Urinalysis Parameters in Predicting Urinary Tract Infection: Does One Size Fit All?

Sonali D Advani et al. Clin Infect Dis. .

Abstract

In a multihospital cohort study of 3392 patients, positive urinalysis parameters had poor positive predictive value for diagnosing urinary tract infection (UTI). Combined urinalysis parameters (pyuria or nitrite) performed better than pyuria alone for ruling out UTI. However, performance of all urinalysis parameters was poor in older women.

Keywords: diagnostic stewardship; leukocyte esterase; nitrite; pyuria; reflex urine cultures.

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Conflict of interest statement

Potential conflicts of interest. S. D. A. and R. N. report support from the Centers for Disease Control and Prevention (SHEPheRD 75D30121D12733-D5-E003) and the Duke Claude D. Pepper Older Americans Independence Center (National Institute on Aging grant number P30AG028716). S. D. A. also reports support from the Society for Healthcare Epidemiology of America, as well as consulting fees from Locus Biosciences (ended), Sysmex America (ended), GlaxoSmithKline, bioMérieux, and the Infectious Diseases Society of America.. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

References

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