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Review
. 2024 Apr 4;13(4):329.
doi: 10.3390/antibiotics13040329.

Antibiotic Stewardship in Surgical Departments

Affiliations
Review

Antibiotic Stewardship in Surgical Departments

Irene Kourbeti et al. Antibiotics (Basel). .

Abstract

Antimicrobial resistance (AMR) has emerged as one of the leading public health threats of the 21st century. New evidence underscores its significance in patients' morbidity and mortality, length of stay, as well as healthcare costs. Globally, the factors that contribute to antimicrobial resistance include social and economic determinants, healthcare governance, and environmental interactions with impact on humans, plants, and animals. Antimicrobial stewardship (AS) programs have historically overlooked surgical teams as they considered them more difficult to engage. This review aims to summarize the evolution and significance of AS in surgical wards, including the surgical intensive care unit (SICU) and the role of diagnostic stewardship (DS). The contribution of AS team members is presented. The new diagnostic modalities and the new technologies including artificial intelligence (AI) are also reviewed.

Keywords: antimicrobial resistance; antimicrobial stewardship; biomarkers; diagnostic stewardship; surgical antibiotic prophylaxis; surgical site infections.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Reasons that lead to improper use of antibiotics in surgical wards.

References

    1. Rice L.B. The Maxwell Finland Lecture: For the Duration- Rational Antibiotic Administration in an Era of Antimicrobial Resistance and Clostridium Difficile. Clin. Infect. Dis. 2008;46:491–496. doi: 10.1086/526535. - DOI - PubMed
    1. Sartelli M., Labricciosa F., Coccolini F., Coimbra R., Zidan F., Ansaloni L., Al-Hasan M., Ansari S., Barie P., Cainzos M., et al. It is time to define an organizational model for the prevention and management of infections along the surgical pathway: A world-wide cross-sectional survey. World J. Emerg. Surg. 2022;17:17. doi: 10.1186/s13017-022-00420-4. - DOI - PMC - PubMed
    1. Antimicrobial Resistance Collaborators Global burden of bacterial antimicrobial resistance in 2019: A systematic analysis. Lancet. 2022;399:629–655. doi: 10.1016/S0140-6736(21)02724-0. - DOI - PMC - PubMed
    1. Menz B., Charani E., Gordon D., Leather A., Moonesinghe D., Phillips C. Surgical Antibiotic prophylaxis in an era of antibiotic resistance: Common resistant bacteria and wider considerations for practice. Infect. Drug Resist. 2021;14:5235–5252. doi: 10.2147/IDR.S319780. - DOI - PMC - PubMed
    1. Spellberg B., Rice L.B. Duration of antibiotic therapy: Shorter is Better. Arch. Intern. Med. 2019;171:210–211. doi: 10.7326/M19-1509. - DOI - PMC - PubMed