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. 2024 Jun 27;143(26):2804-2807.
doi: 10.1182/blood.2024024452.

High efficacy of CD19 CAR T cells in patients with transformed Waldenström macroglobulinemia

Eric Durot  1 , Damien Roos-Weil  2 , Adrien Chauchet  3 , Justine Decroocq  4 , Roberta Di Blasi  5 , Thomas Gastinne  6 , Hedi Bensaber  7 , Morgane Cheminant  8 , Caroline Jacquet  9 , Stéphanie Guidez  10 , François-Xavier Gros  11 , Emmanuel Bachy  12 , Arthur Coste  1 , Pascale Cony-Makhoul  13 , Steven P Treon  14 , Alain Delmer  1 , Ran Reshef  15 , Steven Le Gouill  16 , Jorge J Castillo  14 , Roch Houot  17
Affiliations

High efficacy of CD19 CAR T cells in patients with transformed Waldenström macroglobulinemia

Eric Durot et al. Blood. .

Abstract

Histologic transformation of Waldenström macroglobulinemia (HT-WM) carries a poor prognosis with standard treatments. Here, we report the first series of HT-WM treated with chimeric antigen receptor T cells showing a high efficacy and no unexpected toxicity.

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