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. 2024 Apr 15;14(8):1188.
doi: 10.3390/ani14081188.

Preliminary Results on the Effects of Soybean Isoflavones on Growth Performance and Ruminal Microbiota in Fattening Goats

Yuexin Shao  1 , Junhong Xu  2 , Mengyu Wang  1 , Yalun Ren  1 , Manhong Wei  3 , Bowen Tian  1 , Jun Luo  1 , Juan J Loor  4 , Huaiping Shi  1
Affiliations

Preliminary Results on the Effects of Soybean Isoflavones on Growth Performance and Ruminal Microbiota in Fattening Goats

Yuexin Shao et al. Animals (Basel). .

Abstract

Soybean isoflavones (SIFs), a group of secondary metabolites, have antioxidant, anti-inflammatory, and hormone-like activities. Supplementation with SIFs in the diet was reported to promote lactation performance in ruminants. The present study was performed to further decipher the effect of various concentrations of SIFs on growth and slaughter performance, serum parameters, meat quality, and ruminal microbiota in fattening goats. After a two-week acclimation, a total of 27 5-month-old Guanzhong male goats (18.29 ± 0.44 kg) were randomly assigned to control (NC), 100 mg/d SIF (SIF1), or 200 mg/d SIF (SIF2) groups. The experimental period lasted 56 days. The weight of the large intestine was greater (p < 0.05) in the SIF1 and SIF2 groups compared with the NC group. Meat quality parameters indicated that SIF1 supplementation led to lower (p < 0.05) cooking loss and shear force (0.05 < p < 0.10). The 16S rRNA sequencing analysis demonstrated that SIF1 supplementation led to lower (p < 0.05) proportions of Papillibacter and Prevotellaceae_UCG-004 but greater (p < 0.05) CAG-352 abundance in the rumen; these responses might have contributed to the improvement in production performance. In conclusion, meat quality and ruminal microbiome could be manipulated in a positive way by oral supplementation with 100 mg/d of SIFs in fattening goats. Thus, this study provides new insights and practical evidence for the introduction of SIFs as a novel additive in goat husbandry.

Keywords: fattening goats; growth performance; ruminal microflora; soybean isoflavones.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as potential conflicts of interest.

Figures

Figure 1
Figure 1
Effects of SIF supplementation on ruminal microbiota diversity in goats. (A) Dilution curve; (B) Venn diagram; (C) α-diversity; and (D) PCOA. * p < 0.05.
Figure 2
Figure 2
Effects of SIF supplementation on ruminal microbiota composition in goats. (A) Microbial composition at the phylum level and (B) microbial composition at the genus level.
Figure 3
Figure 3
Predictive functional profiling of 16S rRNA sequencing results. (A) A bar chart of functional prediction; (B) SIF1 vs. NC; and (C) SIF2 vs. NC.
See this image and copyright information in PMC

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