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. 2024 Apr 17;13(8):2310.
doi: 10.3390/jcm13082310.

Real World Data from Catheter Ablation of Ventricular Tachycardias and Premature Ventricular Complexes in a Tertiary Care Center

Christian Schlatzer  1 , Jan Berg  1   2 , Firat Duru  1 , Corinna Brunckhorst  1 , Ardan M Saguner  1 , Laurent M Haegeli  1   2
Affiliations

Real World Data from Catheter Ablation of Ventricular Tachycardias and Premature Ventricular Complexes in a Tertiary Care Center

Christian Schlatzer et al. J Clin Med. .

Abstract

Background: Catheter ablation in patients with ventricular arrhythmias (VA), such as ventricular tachycardias (VT) or frequent premature ventricular complexes (PVC), is increasingly considered an effective and safe therapy when performed in experienced centers. This study sought to determine acute success rates and complication rates of ablation procedures for patients with VA in a Swiss tertiary care center. Methods: All patients who underwent ablation therapy for VT and PVC at the University Heart Center in Zurich, Switzerland, between March 2012 and April 2017 were included in this analysis. Results: A total of 120 patients underwent catheter ablation for VT and PVC (69 and 51, respectively). Seventy percent of patients were male, and the mean age was 55.3 years. The most common indication for ablation was high PVC burden (47.5%), followed by paroxysmal VT (38.3%), ICD shocks (23.3%), incessant VT (12.5%), electrical storm (7.5%), and syncope (3.3%). Acute success rates for VT and PVC ablations were 94.2% and 92.2%, respectively. Rates for complications (including major and minor) for VT and PVC were 10.1% and 7.8%, respectively. Complications occurred only in patients with structural heart disease; no complications were noted in structurally normal hearts. Conclusions: Our results suggest that catheter ablation for VT and PVC has high acute success rates with a reasonable risk for complications in the setting of tertiary care centers, comparable to those reported in other studies.

Keywords: acute success; catheter ablation; clinical outcome; premature ventricular complex; ventricular tachycardia.

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Conflict of interest statement

A.M.S. has received educational grants through his institution from Abbott, Bayer Healthcare, Biosense Webster, Biotronik, Boston Scientific, BMS/Pfizer, and Medtronic; and speaker/advisory board/consulting fees from Bayer Healthcare, Biotronik, Daiichi-Sankyo, Medtronic, Novartis, Pfizer, Stride Bio Inc. and Zoll. L.M.H. has received institutional grants from Abbott, Abiomed, Amgen, Astra Zeneca, Bayer, Biosense Webster, Biotronik, Boston Scientific, Bracco, B. Braun, Daiichi-Sankyo, Edwards, Medtronic, MicroPort, Novartis, Vascular Medical and Zoll. The other authors declare no conflict of interest.

Figures

Figure A1
Figure A1
Differences in acute success rates in VT ablation (ischemic vs. non-ischemic); ns = not significant.
Figure A2
Figure A2
Differences in acute success rates in PVC ablation (no structural heart disease vs. structural heart disease); ns = not significant; HD = heart disease.
Figure 1
Figure 1
An example of substrate mapping in a patient with hemodynamically unstable VT. A large region of areas with low voltage (red) in the inferior left ventricle is shown. Postero-anterior (PA) view.
Figure 2
Figure 2
Ventricular tachycardia termination during RF ablation application at the site of late potentials.
See this image and copyright information in PMC

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