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Review
. 2024 Apr 18;15(4):509.
doi: 10.3390/genes15040509.

Research Progress and Applications of Bovine Genome in the Tribe Bovini

Xingjie Du  1   2 , Yu Sun  1   2 , Tong Fu  1   2 , Tengyun Gao  1   2 , Tianliu Zhang  1   2
Affiliations
Review

Research Progress and Applications of Bovine Genome in the Tribe Bovini

Xingjie Du et al. Genes (Basel). .

Abstract

Various bovine species have been domesticated and bred for thousands of years, and they provide adequate animal-derived products, including meat, milk, and leather, to meet human requirements. Despite the review studies on economic traits in cattle, the genetic basis of traits has only been partially explained by phenotype and pedigree breeding methods, due to the complexity of genomic regulation during animal development and growth. With the advent of next-generation sequencing technology, genomics projects, such as the 1000 Bull Genomes Project, Functional Annotation of Animal Genomes project, and Bovine Pangenome Consortium, have advanced bovine genomic research. These large-scale genomics projects gave us a comprehensive concept, technology, and public resources. In this review, we summarize the genomics research progress of the main bovine species during the past decade, including cattle (Bos taurus), yak (Bos grunniens), water buffalo (Bubalus bubalis), zebu (Bos indicus), and gayal (Bos frontalis). We mainly discuss the development of genome sequencing and functional annotation, focusing on how genomic analysis reveals genetic variation and its impact on phenotypes in several bovine species.

Keywords: adaptive evolution; database; functional genomics; genome annotation; genomics.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships.

Figures

Figure 1
Figure 1
Progress in human and bovine genome projects.
See this image and copyright information in PMC

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