Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2024 Apr 27;42(1):265.
doi: 10.1007/s00345-024-04901-w.

A prospective analysis of thulium laser enucleation in benign prostatic hyperplasia comparing low- and high-power approaches for prostates exceeding 80 g

Ahmed Y Abdelaziz  1 , Islam Kamal  2 , Mahmoud A Abdelhakim  2 , Mostafa Abdelmohsen  2 , Alaa Meshref  2 , Islam Naser  2 , Samer Morsy  2
Affiliations
Randomized Controlled Trial

A prospective analysis of thulium laser enucleation in benign prostatic hyperplasia comparing low- and high-power approaches for prostates exceeding 80 g

Ahmed Y Abdelaziz et al. World J Urol. .

Abstract

Introduction and objectives: To compare the perioperative and functional outcomes of low-power and high-power thulium:YAG VapoEnucleation (ThuVEP) of the prostate for the treatment of large-volume benign prostatic hyperplasia (BPH) (> 80 ml).

Patients and methods: A prospective analysis of 80 patients with symptomatic BPO and prostatic enlargement (more than 80 ml) was conducted. They were divided randomly into two groups (40 patients in each group). One group was treated with low-power ThuVEP, and the other group was treated with high-power ThuVEP. All patients were assessed preoperatively and early postoperatively, and 12-month follow-up data were analyzed. The complications were noted and classified according to the modified Clavien classification system.

Results: The mean age at surgery was 68 (± 6.1) years, and the mean prostate volume was 112 (± 20.1) cc, and there were no differences between the groups (p = 0.457). The mean operative time was 88.4 ± 11.79 min for group A and 93.4 ± 16.34 min for group B, while the mean enucleation time was 59.68 ± 7.24 min for group A and 63.13 ± 10.75 min for group B. There were no significant differences between the groups regarding catheterization time and postoperative stay. The quality of life (QoL), International Prostate Symptom Score (IPSS), maximum urinary flow rate (Qmax), postvoiding residual urine (PVR), and prostate volume improved significantly after treatment and were not significantly different between those treated with the different energies. The incidence of complications was low and did not differ between both the groups.

Conclusion: Low-power ThuVEP is feasible, safe, and effective with comparable results with high-power ThuVEP in the treatment of BPO.

Keywords: Enucleation; High power; Low power; Thulium laser.

PubMed Disclaimer

Conflict of interest statement

The authors declare no funds.

Figures

Fig. 1
Fig. 1
Consort figure: The total number of eligible patients and the number of analyzed patients at the end of the study
See this image and copyright information in PMC

References

    1. Xia SJ, Zhang YN, Lu J et al (2005) Thulium laser resection of prostate-tangerine technique in treatment of benign prostate hyperplasia. Zhonghua Yi Xue Za Zhi 85(45):3225–3228 - PubMed
    1. Enikeev D, Taratkin M (2023) Thulium fiber laser: bringing lasers to a whole new level. Eur Urol Open Sci 48:31–33. 10.1016/j.euros.2022.07.007 - PMC - PubMed
    1. Enikeev D, Glybochko P, Rapoport L et al (2018) A randomized trial comparing the learning curve of 3 endoscopic enucleation techniques (HoLEP, ThuFLEP, and MEP) for BPH using mentoring approach-initial results. Urology 121:51–57. 10.1016/j.urology.2018.06.045 - PubMed
    1. Perri D, Pacchetti A, Morini E, Besana U, Saredi G, Pastore AL, Sighinolfi MC, Rocco B, Micali S, Mazzoleni F, Buizza C, Romero-Otero J, Bruyere F, Herrmann T, Bozzin G (2023) Prognostic factors predicting bleeding after discharge requiring readmission after thulium laser enucleation of the prostate (ThuLEP). Soc Int Urol J 4(5):385–391
    1. Pariser JJ, Famakinwa OJ, Pearce SM, Chung DE (2014) High-power thulium laser vaporization of the prostate: short-term outcomes of safety and effectiveness. J Endourol 28(11):1357–1362. 10.1089/end.2014.0336 - PubMed

Publication types