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. 2024 Sep-Oct;100(5):527-532.
doi: 10.1016/j.jped.2024.03.011. Epub 2024 Apr 24.

Pityriasis lichenoides: assessment of 41 pediatric patients

Aluhine L Fatturi  1 , Mariana A P Morgan  2 , Jandrei R Markus  2 , Lucero Noguera-Morel  3 , Vânia O Carvalho  2
Affiliations

Pityriasis lichenoides: assessment of 41 pediatric patients

Aluhine L Fatturi et al. J Pediatr (Rio J). 2024 Sep-Oct.

Abstract

Objectives: This study aims to evaluate the characteristics and treatment response of patients with pityriasis lichenoides seen in the last 43 years in a pediatric dermatology service.

Methods: This was a retrospective, analytical, longitudinal study of patients under 15 years of age. The medical records were reviewed and data were presented as frequencies, means and variances. Student's t-test, Mann-Whitney test, Fisher's exact test, Pearson/Yates chi-square test and multivariate logistic regression model were used, with p < 0.05 considered.

Results: 41 patients were included, 32 (78.0%) with pityriasis lichenoides chronica (PLC), five (12.2%) with pityriasis lichenoides et varioliformis acuta (PLEVA) and four (9.8%) with clinical PLC without biopsy. The age range of school children and adolescents was 19 (46.3%) and 13 (31.7%) respectively and 27 (65.8%) were male. Two peaks of the highest frequency were observed between 2004 and 2006 (10 patients - 24.4%) and another between 2019 and 2021 (6 patients - 14.7%). There was remission in 71.9% (n = 23), with 56.6% (n = 17) of those who used antibiotic therapy and 80% (n = 4) of those who had phototherapy. The chance of remission was 13 times greater in patients with disease onset after 5 years of age.

Conclusions: The clinical form most commonly found was PLC mainly in school children and adolescents. The frequency peaks coincided with infectious outbreaks. The remission rate was satisfactory with antibiotic therapy, but higher with phototherapy. Remission was greater in patients with disease onset after 5 years of age.

Keywords: Child; Clinical diagnosis; Pityriasis lichenoides; Treatment.

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Conflict of interest statement

Conflicts of interest Aluhine Lopes Fatturi, Mariana Aparecida Pasa Morgan, Lucero Noguera Morel and Jandrei Rogerio Markus has nothing to declare. Vânia Oliveira de Carvalho has been an investigator of Sanofi Genzyme and speaker for Expanscience, Johnson & Johnson Consumer Health, Galderma, Mantecorp, Megalabs and Royal Canin.

Figures

Fig 1
Figure 1
Frequency distribution of pityriasis lichenoides. (A) Distribution from 1980 to 2023. (B) Distribution according to the seasons of the year. (C) Probability of remission of pityriasis lichenoides according to the age at disease onset.
Fig 2
Figure 2
Progress of the patients evaluated according to the treatment used.
See this image and copyright information in PMC

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