Medicinal Plants in the Treatment of Myocardial Infarction Disease: A Systematic Review

Abstract

Background: Myocardial infarction (MI), also referred to as a "heart attack," is brought on by a partial or total interruption of blood supply to the myocardium. Myocardial infarction can be "silent," go undiagnosed, or it can be a catastrophic occurrence that results in hemodynamic decline and untimely death. In recent years, herbal remedies for MI have become effective, secure, and readily accessible.

Objective: The purpose of this review was to examine the medicinal plants and phytochemicals that have been used to treat MI in order to assess the potential contribution of natural substances to the development of herbal MI treatments.

Methodology: A literature search was employed to find information utilizing electronic databases, such as Web of Science, Google Scholar, PubMed, Sci Finder, Reaxys, and Cochrane.

Results: The identification of 140 plants from 12 families led to the abstraction of data on the plant families, parts of the plant employed, chemical contents, extracts, model used, and dose.

Conclusion: The majority of the MI plants, according to the data, belonged to the Fabaceae (11%) and Asteraceae (9%) families, and the most prevalent natural components in plants with MI were flavonoids (43%), glucosides (25%), alkaloids (23%), phenolic acid (19%), saponins (15%), and tannins (12%).

Keywords: Fabaceae; Myocardial infarction; alkaloids.; coronary artery; glucosides; phytochemicals.

Fig. (1)

PRISMA 2020 flow diagram for new systematic reviews, which included searches of databases and registers only.

Fig. (2)

The chemical structure of some potential natural compounds with MI activity.

Fig. (3)

Chemical constituents.

Fig. (4)

Plant extract types.

Fig. (5)

Plant parts used.

Fig. (6)

Plant family analysis.