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Case Reports
. 2024 Apr 1;7(3):266-269.
doi: 10.1002/iju5.12720. eCollection 2024 May.

A case of testicular cancer in a long-term hydranencephaly survivor with undescended testes

Wataru Hirata  1 , Toshiaki Shinojima  1 , Kotaro Yokota  1 , Rei Kin  2 , Taketo Yamada  2 , Hirotaka Asakura  1
Affiliations
Case Reports

A case of testicular cancer in a long-term hydranencephaly survivor with undescended testes

Wataru Hirata et al. IJU Case Rep. .

Abstract

Introduction: The development of malignant tumors in patients with hydranencephaly is extremely rare. We describe the first case of testicular cancer that developed in the undescended testes of a long-term survivor of hydranencephaly.

Case presentation: A 32-year-old man with severe cerebral palsy due to hydranencephaly was referred to our department for the evaluation of a subcutaneous lump in the lower right abdomen. He was a long-term survivor of hydranencephaly. After confirming the diagnosis of right testicular cancer originating in his undescended testes, surgical resection was performed. Pathological examination revealed a mixed-type germ cell tumor.

Conclusion: The decision-making process for treating malignant tumors, like testicular cancer, in adults with severe cerebral palsy can be challenging. Clinical ethics consultation could be helpful in avoiding treatment delays.

Keywords: cerebral palsy; hydranencephaly; testicular cancer; undescended testes.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Brain CT scan showing complete replacement of the cerebral hemispheres with fluid.
Fig. 2
Fig. 2
Pelvic CT images. (a) A 10‐cm well‐circumscribed oval tumor (white arrowheads). (b) An image of the bilateral UDT (white arrowheads) obtained 4 years ago.
Fig. 3
Fig. 3
Gross and microscopic findings of testicular tumor. (a) A complete resection of the tumor with the testis and spermatic cord. (b) A magnification view of the immature teratoma component shows the presence of tubular structures and cartilage (H&E staining, ×200; scale bar = 100 μm). (c) A solid pattern of embryonal cell carcinoma (H&E, ×200; scale bar = 100 μm).
See this image and copyright information in PMC

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