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. 2024 Apr;105(4):001974.
doi: 10.1099/jgv.0.001974.

ICTV Virus Taxonomy Profile: Nairoviridae 2024

Jens H Kuhn  1 , Sergey V Alkhovsky  2 , Tatjana Avšič-Županc  3 , Éric Bergeron  4 , Felicity Burt  5 , Koray Ergünay  6   7   8   9 , Aura R Garrison  10 , Marco Marklewitz  11 , Ali Mirazimi  12 , Anna Papa  13 , Janusz T Pawęska  14 , Jessica R Spengler  4 , Gustavo Palacios  15
Affiliations

ICTV Virus Taxonomy Profile: Nairoviridae 2024

Jens H Kuhn et al. J Gen Virol. 2024 Apr.

Abstract

Nairoviridae is a family for negative-sense RNA viruses with genomes of about 17.2-21.1 kb. These viruses are maintained in and/or transmitted by arthropods among birds, reptiles and mammals. Norwaviruses and orthonairoviruses can cause febrile illness in humans. Several orthonairoviruses can infect mammals, causing mild, severe and sometimes, fatal diseases. Nairovirids produce enveloped virions containing two or three single-stranded RNA segments with open reading frames that encode a nucleoprotein (N), sometimes a glycoprotein precursor (GPC), and a large (L) protein containing an RNA-directed RNA polymerase (RdRP) domain. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) report on the family Nairoviridae, which is available at www.ictv.global/report/nairoviridae.

Keywords: ICTV Report; Nairoviridae; nairovirid; nairovirus; orthonairovirus; taxonomy.

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Conflict of interest statement

The authors declare that there are no conflicts of interest.

Figures

Fig. 1.
Fig. 1.. (a) Transmission electron micrograph of a Crimean-Congo hemorrhagic fever virus particle, magnification 50 000× (courtesy of Mateja Poljšak-Prijatelj and Marko Kolenc, Institute of Microbiology and Immunology, Ljubljana, Slovenia). (b) Illustration of a nairovirid particle.
Fig. 2.
Fig. 2.. Nairovirid genome. GPC, glycoprotein precursor gene; L, large protein gene; N, nucleoprotein gene.
See this image and copyright information in PMC

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