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Review
. 2024 May-Jun;38(3):1000-1008.
doi: 10.21873/invivo.13533.

Proteomics in Psoriasis: Recent Advances

Georgios Leotsakos  1 , Ioannis Katafigiotis  2 , Ioannis Leotsakos  3 , Fiori Kousta  4 , Aristeidis Molympakis  4 , Aikaterini Perimeni  5 , Michael Koutsilieris  6
Affiliations
Review

Proteomics in Psoriasis: Recent Advances

Georgios Leotsakos et al. In Vivo. 2024 May-Jun.

Abstract

Psoriasis continues to affect a large percentage of patients worldwide and strongly appears to be a systematic disease. Efforts are being made to understand its etiology, which have led to research extended to genomic analysis with a focus on the role of pro-inflammatory cytokines, which play a major role in the pathogenesis of the disease. Plasma proteomic analysis in various diseases has provided promising results for choosing the right treatment for psoriasis, suggesting that it could play a key role in the prevention, prognosis, and treatment of the disease by individualizing treatment choices based on the proteomic profile of each patient. In this review, we focus on existing data in the bibliography on proteomic analysis in psoriasis and relevant approaches to future targeted therapies.

Keywords: Psoriasis; biomarkers; genomics; proteomics; review.

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Conflict of interest statement

The Authors declare no conflicts of interest in relation to this study.

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