Review
[An introduction to synthetic progestogens pharmacology (author's transl)]
[Article in
French]
- PMID: 386914
Item in Clipboard
Review
[An introduction to synthetic progestogens pharmacology (author's transl)]
[Article in
French]
Ann Endocrinol (Paris).
1979.
Abstract
Synthetic progestins differ in their progestomimetic and other endocrine effects. Their affinities for different steroid hormone receptors have been measured and their pharmacological activities (progestomimetic, uterotrophic, anti-estrogenic, androgen and anti-gonadotrophic) have been evaluated concomitantly. Derivatives of the pregnane series are basically progestomimetic only, whereas derivatives of the norandrostane series have distinctly androgenic and anti-estrogenic properties. A knowledge of these various activities facilitates the choice of an appropriate therapy.
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