Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Jul-Aug;36(4):229-230.
doi: 10.25259/NMJI_283_20.

Diabetic striatopathy in an adult with ketotic hyperglycaemia

Eram Nahid  1 , Saumya Gupta  1 , Kshitij Prasad  1 , Anish Kumar Saha  1 , Mukti Prakash Meher  1 , L P Meena  1
Affiliations
Case Reports

Diabetic striatopathy in an adult with ketotic hyperglycaemia

Eram Nahid et al. Natl Med J India. 2023 Jul-Aug.

Abstract

Diabetic striatopathy (DS) is a rare and life-threatening mani- festation of diabetes. The disease commonly affects individuals of Asian descent, women and the elderly. DS is characterized by dyskinesias with basal ganglia hyperintensities on imaging. Despite being rare, prompt recognition of a hyperglycaemia- induced hemichorea-hemiballismus is essential because the symptoms are reversible with correction of hyperglycaemia. Diagnosis is based on blood analysis and neuroimaging findings. Laboratory tests reveal raised glycosylated haemoglobin (HbA1c) levels, which indicate poorly controlled diabetes. Neuroimaging provides suggestive findings of DS. It is usually associated with non-ketotic hyperglycaemia. We report a 50-year-old woman who presented with ketotic hyperglycaemia and left-sided hemichorea and partial seizures with secondary generalization.

PubMed Disclaimer

References

    1. Chua CB, Sun CK, Hsu CW, Tai YC, Liang CY, Tsai IT,. 'Diabetic striatopathy': Clinical presentations, controversy, pathogenesis, treatments, and outcomes. Sci Rep. 2020; 10:1594
    1. Khan I, Kant C, Sanwaria A, Goyal A,. Hemichorea-hemiballismus as the presenting manifestation of nonketotic hyperglycemia in an adolescent with undiagnosed type 2 diabetes mellitus. Indian J Endocrinol Metab. 2012; 16: (Suppl 1) S129-S131
    1. Bizet J, Cooper CJ, Quansah R, Rodriguez E, Teleb M, Hernandez GT,. Chorea, hyperglycemia, basal ganglia syndrome (C-H-BG) in an uncontrolled diabetic patient with normal glucose levels on presentation. Am J Case Rep. 2014; 15: 143-6
    1. Oh SH, Lee KY, Im JH, Lee MS,. Chorea associated with nonketotic hyperglycemia and hyperintensity basal ganglia lesion on T1-weighted brain MRI study: A meta-analysis of 53 cases including four present cases. J Neurol Sci. 2002; 200:57-62
    1. Bathla G, Policeni B, Agarwal A,. Neuroimaging in patients with abnormal blood glucose levels. AJNR Am J Neuroradiol. 2014; 35:833-40

Publication types

Substances

LinkOut - more resources