Autonomic Dysfunction from Diagnosis to Treatment
- PMID: 38692780
- DOI: 10.1016/j.pop.2024.02.006
Autonomic Dysfunction from Diagnosis to Treatment
Abstract
Autonomic disorders can present with hypotension, gastrointestinal, genitourinary symptoms, and heat intolerance. Diabetes is the most common causes of autonomic failure, and management should focus on glucose control to prevent developing autonomic symptoms. The most prevalent cause of dysautonomia, or autonomic dysfunction, is Postural Orthostatic Tachycardia Syndrome (POTS). Autonomic testing characterizes causes for nonspecific symptoms but is not necessary in patients with classic presentations. Treatment for autonomic dysfunction and failure focus on discontinuing offending medications, behavioral modification, and pharmacologic therapy to decrease symptom severity. Autonomic failure has no cure; therefore, the focus remains on improving quality of life.
Keywords: Autonomic disorders; Autonomic nervous system; Autonomic testing; Neurogenic orthostatic hypotension; Postural orthostatic tachycardia syndrome.
Copyright © 2024 Elsevier Inc. All rights reserved.
Conflict of interest statement
Disclosure Dr A.C. Peltier has accepted compensation for consultation, speaking fees, from Astra Zeneca, Alnylam pharmaceutical companies. Dr A.C. Peltier has research support from CSL Behring, United States for investigator-initiated study, and NIH. None of these disclosures is relative to this document.
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