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. 2024 Apr 17:15:1321611.
doi: 10.3389/fpsyt.2024.1321611. eCollection 2024.

Assessing the Quick Inventory of Depressive Symptomatology Self-Report scores to predict continuous employment in mood disorder patients

Yasuyuki Matsumoto  1 , Hitoshi Sakurai  1 , Yumi Aoki  2 , Yoshikazu Takaesu  3 , Isa Okajima  4 , Hisateru Tachimori  5 , Masami Murao  1 , Taku Maruki  1 , Takashi Tsuboi  1 , Koichiro Watanabe  1
Affiliations

Assessing the Quick Inventory of Depressive Symptomatology Self-Report scores to predict continuous employment in mood disorder patients

Yasuyuki Matsumoto et al. Front Psychiatry. .

Abstract

Objective: Depression significantly impacts the job performance and attendance of workers, leading to increased absenteeism. Predicting occupational engagement for individuals with depression is of paramount importance. This study aims to determine the cut-off score which predicts continuous employment for patients with mood disorders using the Quick Inventory of Depressive Symptomatology, Self-Report (QIDS-SR).

Methods: In a prospective observational trial conducted in Tokyo, 111 outpatients diagnosed with either major depressive disorder or bipolar depression were enrolled. Their employment statuses of these participants were tracked over a six-month period after their QIDS-SR scores were recorded. Based on their employment trajectories, participants were categorized into either continuous or non-continuous employment groups. Binary logistic regression was applied to examine the relationship between the QIDS-SR scores and employment outcomes, with adjustments for age, gender, and psychiatric diagnoses. Receiver operating characteristic curves were utilized to identify the optimal QIDS-SR cut-off values for predicting continuous employment.

Findings: Binary logistic regression demonstrated that a lower score on the QIDS-SR was linked to an elevated likelihood of continuous employment (adjusted odds ratio 1.15, 95% CI: 1.06-1.26, p=0.001). The optimal cut-off point, determined by the Youden Index, was 10/11, showcasing a 63% sensitivity and 71% specificity.

Conclusion: The results emphasize the potential of the QIDS-SR as a prognostic instrument for predicting employment outcomes among individuals with depressive disorders. These findings further underscore the importance of managing depressive symptoms to mild or lower intensities to ensure ongoing employment.

Keywords: QIDS-SR; absenteeism; bipolar; depression; employment; severity.

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Conflict of interest statement

YM received honorarium from Sumitomo Pharma, Janssen Pharmaceutical, and Meiji Seika Pharma. HS received grants from Japan Society for the Promotion of Science, Japan Research Foundation Clinical Pharmacology, and Takeda Science Foundation, and honorarium from Eisai, Takeda Pharmaceutical, Otsuka Pharmaceutical, Meiji Seika Pharma, Shionogi Pharma, Yoshitomiyakuhin, Sumitomo Pharma, Kyowa Pharmaceutical, MSD, and Lundbeck Japan. YA received honorarium from Eisai, Sumitomo Pharma, Meiji Seik Pharma, and Viatris. YT received honorarium from Eisai, Sumitomo Pharma, Takeda Pharmaceutical, Meiji Seika Pharma, Shionogi, MSD, and Otsuka Pharmaceutical. IO received grants from NEC solution Innovators Ltd and Infocom Co, consulting fees from NEC solution Innovators Ltd and Suntory Wellness Ltd, and honorarium from Otsuka Pharmaceutical Co., Ltd., MSD LLC, and Eisai Co., Ltd. HT belongs to an endowed course funded by the Takeda Pharmaceutical Company Limited, and belongs to a department that accepts financial support from National Clinical Database, Johnson & Johnson K.K, Nipro Corporation, and Intuitive Surgical Sàrl. MM received honorarium from Yoshitomiyakuhin. TM received honorarium from Sumitomo Pharma. TT received honorarium from Takeda Pharmaceutical, Otsuka Pharmaceutical, Meiji Seika Pharma, Shionogi Pharma, Yoshitomiyakuhin, Sumitomo Pharma, Kyowa Pharmaceutical, MSD, Nippon Boehringer lngelheim, Mylan EPD, Mitsubishi Tanabe Pharma, Viatris, Mochida Pharmaceutical, Janssen Pharmaceutical, TEIJIN PHARMA, and Lundbeck Japan. KW is a consultant of Boehringer Ingelheim, Daiichi Sankyo, Eisai, Eli Lilly, Janssen Pharmaceutical, Kyowa Pharmaceutical, Lundbeck Japan, Luye Pharma, Mitsubishi Tanabe Pharma, Otsuka Pharmaceutical, Pfizer, Sumitomo Dainippon Pharma, Taisho Toyama Pharmaceutical, and Takeda Pharmaceutical.

Figures

Figure 1
Figure 1
Receiver operating characteristic curve for the QIDS-SR score to predict continuous employment. QIDS-SR, the 16-Item Quick Inventory of Depressive Symptomatology, Self-Report.
See this image and copyright information in PMC

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