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Review
. 2024 Apr 30;16(4):e59385.
doi: 10.7759/cureus.59385. eCollection 2024 Apr.

Beyond the Pump: A Narrative Study Exploring Heart Memory

Affiliations
Review

Beyond the Pump: A Narrative Study Exploring Heart Memory

Abdulkreem Al-Juhani et al. Cureus. .

Abstract

The field of organ transplantation, particularly heart transplantation, has brought to light interesting phenomena challenging traditional understandings of memory, identity, and consciousness. Studies indicate that heart transplant recipients may exhibit preferences, emotions, and memories resembling those of the donors, suggesting a form of memory storage within the transplanted organ. Mechanisms proposed for this memory transfer include cellular memory, epigenetic modifications, and energetic interactions. Moreover, the heart's intricate neural network, often referred to as the "heart brain," communicates bidirectionally with the brain and other organs, supporting the concept of heart-brain connection and its role in memory and personality. Additionally, observations from hemispherectomy procedures highlight the brain's remarkable plasticity and functional preservation beyond expectations, further underscoring the complex interplay between the brain, body, and identity. However, ethical and philosophical questions regarding the implications of these findings, including the definition of death and the nature of personal identity, remain unresolved. Further interdisciplinary research is needed to unravel the intricacies of memory transfer, neuroplasticity, and organ integration, offering insights into both organ transplantation and broader aspects of neuroscience and human identity. Understanding these complexities holds promise for enhancing patient care in organ transplantation and deepens our understanding of fundamental aspects of human experience and existence.

Keywords: cardiac transplantation; cellular memory; heart-brain connection; organ transplantation; personal identity.

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Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. How feelings of stereotype threat influence older adults' memory performance. Chasteen AL, Bhattacharyya S, Horhota M, Tam R, Hasher L. https://doi.org/10.1080/03610730590948177. Exp Aging Res. 2005;31:235–260. - PMC - PubMed
    1. Hashim HT, Ahmed N, Faggian G, Manyalich M, Onorati F. Heart Transplantation.Cham: Springer International Publishing. Cham: Springer International Publishing; 2022. Heart Transplantation; pp. 10–1007.
    1. Personality changes following heart transplantation: the role of cellular memory. Liester MB. Med Hypotheses. 2020;135:109468. - PubMed
    1. The memory of the heart. Cirillo M. https://doi.org/10.3390/jcdd5040055. J Cardiovasc Dev Dis. 2018;5:55. - PMC - PubMed
    1. Heart versus head: do judges follow the law of follow their feelings. Wistrich AJ, Guthrie C, Rachlinski JJ. https://heinonline.org/HOL/LandingPage?handle=hein.journals/tlr93&div=30... Tex Rev. 2014

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