Norepinephrine salt formulations are not a matter of pharmacologic potency

Patrick M Wieruszewski^{1

2}, Ashish K Khanna^{3

4}

Affiliations

¹ Department of Pharmacy, Mayo Clinic, RO_MB_GR_722PH, 200 First Street SW, Rochester, MN, 55905, USA. wieruszewski.patrick@mayo.edu.
² Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA. wieruszewski.patrick@mayo.edu.
³ Department of Anesthesiology, Section on Critical Care Medicine, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, NC, USA.
⁴ Outcomes Research Consortium, Cleveland, OH, USA.

Patrick M Wieruszewski et al. Intensive Care Med. 2024 Jul.

. 2024 Jul;50(7):1179-1180.

doi: 10.1007/s00134-024-07451-2. Epub 2024 May 2.

Patrick M Wieruszewski^{1

2}, Ashish K Khanna^{3

4}

¹ Department of Pharmacy, Mayo Clinic, RO_MB_GR_722PH, 200 First Street SW, Rochester, MN, 55905, USA. wieruszewski.patrick@mayo.edu.
² Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA. wieruszewski.patrick@mayo.edu.
³ Department of Anesthesiology, Section on Critical Care Medicine, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, NC, USA.
⁴ Outcomes Research Consortium, Cleveland, OH, USA.

No abstract available

References

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1. Wieruszewski PM, Leone M, Kaas-Hansen BS et al (2024) Position paper on the reporting of norepinephrine formulations in critical care from the society of critical care medicine and european society of intensive care medicine joint task force. Crit Care Med 52:521–530. https://doi.org/10.1097/CCM.0000000000006176 - DOI - PubMed
1. Kenakin T, Williams M (2014) Defining and characterizing drug/compound function. Biochem Pharmacol 87:40–63. https://doi.org/10.1016/j.bcp.2013.07.033 - DOI - PubMed
1. Currigan DA, Hughes RJA, Wright CE et al (2014) Vasoconstrictor responses to vasopressor agents in human pulmonary and radial arteries: an in vitro study. Anesthesiology 121:930–936. https://doi.org/10.1097/ALN.0000000000000430 - DOI - PubMed
1. Wieruszewski PM (2023) Norepinephrine dosage: the details go beyond a grain of salt. Intensive Care Med 49:714–715. https://doi.org/10.1007/s00134-023-07077-w - DOI - PubMed