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Review
. 2024 May 2;316(5):146.
doi: 10.1007/s00403-024-02861-0.

Malignant melanoma arising in a burn scar

Emily Ma  1 , Shealinna Ge  2 , Walter L Rush  3 , Jill Allbritton  4
Affiliations
Review

Malignant melanoma arising in a burn scar

Emily Ma et al. Arch Dermatol Res. .

Abstract

Secondary malignancies are rare but devastating complications of longstanding burn scars. Squamous cell carcinoma is the most common, followed by basal cell carcinoma and melanomas. There are fewer than 50 total reported cases of malignant melanomas arising in burn scars. We report a case of malignant melanoma arising within a longstanding burn scar confirmed by histology, FISH, and PRAME staining to further characterize melanomas arising in burn scars and to illustrate the diagnostic challenges they present.

Keywords: Burn; FISH; Melanoma; PRAME; Scar.

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