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. 2024 May 2;24(1):148.
doi: 10.1186/s12883-024-03606-2.

Assessing the impact of migraine on benign paroxysmal positional vertigo symptoms and recovery

Seda Çakır  1 , Aysenur Sahin  1 , Ozlem Gedik-Soyuyuce  2 , Zeynep Gence Gumus  2 , İbrahim Sertdemir  3 , Nazım Korkut  4 , Pınar Yalınay Dikmen  5
Affiliations

Assessing the impact of migraine on benign paroxysmal positional vertigo symptoms and recovery

Seda Çakır et al. BMC Neurol. .

Abstract

Background: During episodes of benign paroxysmal positional vertigo (BPPV), individuals with migraine, compared with individuals without migraine, may experience more severe vestibular symptoms because of their hyperexcitable brain structures, more adverse effects on quality of life, and worse recovery processes from BPPV.

Methods: All patients with BPPV were assigned to the migraine group (MG, n = 64) and without migraine group (BPPV w/o MG, n = 64) and completed the Vertigo Symptom Scale (VSS), Vertigo Dizziness Imbalance Symptom Scale (VDI-SS), VDI Health-Related Quality of Life Scale (VDI-HRQoLS), Beck Anxiety Inventory (BAI), and Beck Depression Inventory (BDI) at the time of BPPV diagnosis (baseline) and on the one-month follow-up. Headache Impact Test-6 and Migraine Disability Assessment Scale were used for an assessment of headache. Motion sickness was evaluated based on the statement of each patient as present or absent.

Results: Compared with the BPPV w/o MG, the MG had higher VSS scores at baseline [19.5 (10.7) vs. 11.3 (8.5); p < 0.001] and on one-month follow-up [10.9 (9.3) vs. 2.2 (2.7), p < 0.001]; experienced more severe dizziness and imbalance symptoms based on the VDI-SS at baseline (61.9% vs. 77.3%; p < 0.001) and after one month (78.9% vs. 93.7%, p < 0.001); and more significantly impaired quality of life according to the VDI-HRQoLS at baseline (77.4% vs. 91.8%, p < 0.001) and after one month (86.3% vs. 97.6%, p < 0.001). On the one-month follow-up, the subgroups of patients with moderate and severe scores of the BAI were higher in the MG (39.2%, n = 24) than in the BPPV w/o MG (21.8%, n = 14) and the number of patients who had normal scores of the BDI was lower in the MG than in the BPPV w/o MG (67.1% vs. 87.5%, p = 0.038).

Conclusion: Clinicians are advised to inquire about migraine when evaluating patients with BPPV because it may lead to more intricate and severe clinical presentation. Further studies will be elaborated the genuine nature of the causal relationship between migraine and BPPV.

Keywords: BPPV; Benign paroxysmal positional vertigo; Dizziness; Migraine; Vertigo.

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Conflict of interest statement

The authors declare no competing interests.

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References

    1. Group GBDNDC. Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the global burden of disease study 2015. Lancet Neurol. 2017;16(11):877–897. - PMC - PubMed
    1. Sprenger T, Borsook D. Migraine changes the brain: neuroimaging makes its mark. Curr Opin Neurol. 2012;25(3):252–262. doi: 10.1097/WCO.0b013e3283532ca3. - DOI - PMC - PubMed
    1. Coppola G, Chen W-T. Neurophysiology of the Migraine Brain: Springer; 2021.
    1. Schwedt TJ, Chiang CC, Chong CD, Dodick DW. Functional MRI of migraine. Lancet Neurol. 2015;14(1):81–91. doi: 10.1016/S1474-4422(14)70193-0. - DOI - PMC - PubMed
    1. Denuelle M, Boulloche N, Payoux P, Fabre N, Trotter Y, Geraud G. A PET study of photophobia during spontaneous migraine attacks. Neurology. 2011;76(3):213–218. doi: 10.1212/WNL.0b013e3182074a57. - DOI - PubMed

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