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Review
. 2024 Apr 18:12:1393308.
doi: 10.3389/fchem.2024.1393308. eCollection 2024.

Lab-on-a-molecule and multi-analyte sensing

David C Magri  1
Affiliations
Review

Lab-on-a-molecule and multi-analyte sensing

David C Magri. Front Chem. .

Abstract

The concept of a lab-on-a-molecule, which was proposed just short of two decades ago, has captured the imagination of scientists. From originally being proposed as an AND logic gate driven by three chemical inputs as a direct way of detecting congregations of chemical species, the definition of what constitutes a lab-on-a-molecule has broadened over the years. In this review, molecules that can detect multiple analytes by fluorescence, among other techniques, are reviewed and discussed, in the context of molecular logic and multi-analyte sensing. The review highlights challenges and suggestions for moving the frontiers of research in this field to the next dimension.

Keywords: chemosensor; fluorescence sensing; lab-on-a-molecule; molecular logic gate; multi-analyte detection.

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Conflict of interest statement

The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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