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. 2024 Mar 1;41(2):93-97.
doi: 10.4103/lungindia.lungindia_449_23. Epub 2024 Feb 27.

Accuracy of endobronchial ultrasound (EBUS) in the staging of lung cancer - A comparison of staging EBUS with postoperative pathological nodal staging

Eshita Shah  1 , N Sankara Raman  1 , Manish K Aggarwal  1 , Amit Jain  1 , Arushi Chokhani  1 , Avinash Murugan  1 , Rajiv Goyal  1 , Laengmawia Darlong  2 , Ullas Batra  3
Affiliations

Accuracy of endobronchial ultrasound (EBUS) in the staging of lung cancer - A comparison of staging EBUS with postoperative pathological nodal staging

Eshita Shah et al. Lung India. .

Abstract

Background: Endobronchial ultrasound-guided transbronchial fine-needle aspiration (EBUS-TBNA) has replaced mediastinoscopy as the preferred investigation for evaluating mediastinum in staging lung cancer. There is little evidence of mediastinal staging by EBUS-TBNA from India.

Objectives: To study endobronchial ultrasound's diagnostic accuracy in staging lung cancer.

Methodology: We retrospectively analysed patients operated on for lung cancer where EBUS was performed preoperatively for mediastinal staging. We compared the histological findings obtained from different mediastinal lymph nodes (LNs) by EBUS-TBNA with the pathology of the same LNs obtained after surgical dissection as the reference standard.

Results: Seventy-six patients underwent curative surgery for lung cancer. The diagnostic accuracy, sensitivity, specificity, positive predictive value and negative predictive value of EBUS-TBNA in predicting mediastinal metastasis were 93.9%, 40%, 99%, 80% and 94.6%, respectively. Of the 115 LNs sampled, EBUS-TBNA was false negative in six nodes, resulting in an up-staging of six patients.

Conclusions: EBUS-TBNA has a high diagnostic accuracy for lung cancer staging.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Details of the number of operated patients and lymph nodes sampled by EBUS TBNA finally included in the study
See this image and copyright information in PMC

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